Cerebellum and ocular motor control

A Kheradmand, DS Zee - Frontiers in neurology, 2011 - frontiersin.org
An intact cerebellum is a prerequisite for optimal ocular motor performance. The cerebellum
fine-tunes each of the subtypes of eye movements so they work together to bring and …

Episodic ataxias

JC Jen, J Wan - Handbook of clinical neurology, 2018 - Elsevier
Primary episodic ataxias (EAs) are a group of dominantly inherited disorders characterized
by transient recurrent incoordination and truncal instability, often triggered by physical …

The cerebellum in eye movement control: nystagmus, coordinate frames and disconjugacy

VR Patel, DS Zee - Eye, 2015 - nature.com
In this review we discuss several aspects of eye movement control in which the cerebellum
is thought to have a key role, but have been relatively ignored. We will focus on the …

Evaluation and management of acute acquired comitant esotropia in children

AL Gilbert, EB Koo, G Heidary - Seminars in ophthalmology, 2017 - Taylor & Francis
Acute acquired comitant esotropia (AACE) is characterized by a sudden-onset eye
misalignment with an equal angle of deviation in all fields of gaze. This form of esotropia is …

Eye movements in vestibular disorders

A Kheradmand, AI Colpak, DS Zee - Handbook of clinical neurology, 2016 - Elsevier
The differential diagnosis of patients with vestibular symptoms usually begins with the
question: is the lesion central or is it peripheral? The answer commonly emerges from a …

Vestibular neuroscience for the headache specialist

CD Balaban, RD Black… - Headache: The Journal …, 2019 - Wiley Online Library
Background The vestibular system is a multifaceted, integrative sensory system that is often
referred to as the “multi‐sensory” sense. There is an extensive literature about the vestibular …

Novel CACNA1A mutation causes febrile episodic ataxia with interictal cerebellar deficits

SH Subramony, K Schott, RS Raike… - Annals of Neurology …, 2003 - Wiley Online Library
Abstract Episodic ataxia type 2 (EA2) is a dominantly inherited disorder, characterized by
spells of ataxia, dysarthria, vertigo, and migraines, associated with mutations in the neuronal …

Loss of flocculus purkinje cell firing precision leads to impaired gaze stabilization in a mouse model of spinocerebellar ataxia type 6 (SCA6)

HHV Chang, AA Cook, AJ Watt, KE Cullen - Cells, 2022 - mdpi.com
Spinocerebellar Ataxia Type 6 (SCA6) is a mid-life onset neurodegenerative disease
characterized by progressive ataxia, dysarthria, and eye movement impairment. This …

Latency and initiation of the human vestibuloocular reflex to pulsed galvanic stimulation

ST Aw, MJ Todd, GM Halmagyi - Journal of …, 2006 - journals.physiology.org
Cathodal galvanic currents activate primary vestibular afferents, whereas anodal currents
inhibit them. Pulsed galvanic vestibular stimulation (GVS) was used to determine the latency …

Vestibular impairments in episodic ataxia type 2

JH Choi, EH Oh, SY Choi, HJ Kim, SK Lee, JY Choi… - Journal of …, 2022 - Springer
Abstract Episodic ataxia type 2 (EA2) can present diverse ocular motor abnormalities, but
few studies have systematically evaluated vestibular function during the interictal periods …