Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Metals are essential components in all forms of life required for the function of nearly half of
all enzymes and are critically involved in virtually all fundamental biological processes …

Intracellular lipopolysaccharide from Gram-negative bacteria including Escherichia coli,
Salmonella typhimurium, Shigella flexneri, and Burkholderia thailandensis activates mouse …

Successful solid organ transplantation reflects meticulous attention to the details of
immunosuppression, balancing risks for graft rejection against risks for infection. The “net …

Neutrophils have long been viewed as the final effector cells of an acute inflammatory
response, with a primary role in the clearance of extracellular pathogens. However, more …

Idiopathic Parkinson's disease (iPD) is a movement disorder characterized by the
degeneration of dopaminergic neurons and aggregation of the protein α‐synuclein. Patients …

Neutrophils are the first line of innate immune defense against infectious diseases.
However, since their discovery by Elie Metchnikoff, they have always been considered …

The nuclear factor of activated T cells (NFAT) family of transcription factors, which includes
NFAT1, NFAT2, and NFAT4, are well-known to play important roles in T cell activation. Most …

Neutrophils have long been viewed as short-lived cells crucial for the elimination of
extracellular pathogens, possessing a limited role in the orchestration of the immune …

C-type lectin receptors (CLRs) comprise a heterogeneous group of transmembrane proteins.
Many of them are expressed in myeloid cells and signal in response to pathogen-derived or …