Future antimicrobials: Natural and functionalized phenolics

A Lobiuc, NE Pavăl, II Mangalagiu, R Gheorghiță… - Molecules, 2023 - mdpi.com
With incidence of antimicrobial resistance rising globally, there is a continuous need for
development of new antimicrobial molecules. Phenolic compounds having a versatile …

Therapeutic approach to Alzheimer's disease: current treatments and new perspectives

T Pardo-Moreno, A González-Acedo… - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common cause of dementia. The pathophysiology of
this disease is characterized by the accumulation of amyloid-β, leading to the formation of …

Curcumin sustained release with a hybrid chitosan-silk fibroin nanofiber containing silver nanoparticles as a novel highly efficient antibacterial wound dressing

P Heydari Foroushani, E Rahmani, I Alemzadeh… - Nanomaterials, 2022 - mdpi.com
Drug loading in electrospun nanofibers has gained a lot of attention as a novel method for
direct drug release in an injury site to accelerate wound healing. The present study deals …

Oxidative stress and antioxidants in health and disease

TR Kıran, O Otlu, AB Karabulut - Journal of Laboratory Medicine, 2023 - degruyter.com
The increase in the formation of reactive oxygen and reactive nitrogen species of
endogenous or exogenous origin causes oxidative stress due to pro-oxidant and antioxidant …

Polyphenols as antioxidant/pro-oxidant compounds and donors of reducing species: relationship with human antioxidant metabolism

CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Processes, 2023 - mdpi.com
In this review, we have focused mainly on the study of their antioxidant and pro-oxidant
capacity, and the analysis of the oxidation of the catechol group to o-quinone. The redox …

Iron homeostasis imbalance and ferroptosis in brain diseases

H Long, W Zhu, L Wei, J Zhao - MedComm, 2023 - Wiley Online Library
Brain iron homeostasis is maintained through the normal function of blood–brain barrier and
iron regulation at the systemic and cellular levels, which is fundamental to normal brain …

Drug-loaded carbon nanotube incorporated in nanofibers: a multifunctional nanocomposite for smart chronic wound healing

M Shakiba, P Jahangiri, E Rahmani… - ACS Applied Polymer …, 2023 - ACS Publications
A proper dressing for chronic wounds should be able to preserve moisture while absorbing
the exudates and exhibit good antibacterial properties and reliable mechanical properties …

Recent advances in the treatment of Alzheimer's disease using nanoparticle-based drug delivery systems

P Poudel, S Park - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder.
Most existing treatments only provide symptomatic solutions. Here, we introduce currently …

Antioxidant Metabolism Pathways in Vitamins, Polyphenols, and Selenium: Parallels and Divergences

CMC Andrés, JM Pérez de la Lastra, CA Juan… - International Journal of …, 2024 - mdpi.com
Free radicals (FRs) are unstable molecules that cause reactive stress (RS), an imbalance
between reactive oxygen and nitrogen species in the body and its ability to neutralize them …

Bioinspired self-stratification fouling release silicone coating with strong adhesion to substrate

Y Lin, Y Xie, F Chen, S Gong, W Yang, X Liang… - Chemical Engineering …, 2022 - Elsevier
Silicone-based fouling release coatings (FRCs) are considered to be one of the promising
eco-friendly antifouling technologies, while traditional silicone-based FRCs generally have …