The extracellular domain of plasma membrane integrin αvβ3 contains a cell surface receptor
for thyroid hormone analogues. The receptor is largely expressed and activated in tumor …

Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …

Mutations in the p53 gene are common and occur in over 50% of all cancers, as it is
involved in DNA damage repair, cell cycle regulation and apoptosis. Moreover, the p53 …

In the area of research on neurodegenerative diseases, the current challenge is to search
for appropriate research methods that would detect these diseases at the earliest possible …

The liver plays a central role in the pharmacokinetics of drugs through drug metabolizing
enzymes and transporters. Non-alcoholic steatohepatitis (NASH) causes disease-specific …

Thyroid carcinoma (TC) is the most common endocrine neoplasia, with its incidence
increasing in the last 40 years worldwide. The determination of genetic and/or protein …

Flavivirus is a genus that comprises more than 70 viruses with common characteristics and
causes many of the most prevalent infections in the world. These viruses affect more people …

The activation of the innate and the adaptive immune responses contributes to the control
and eradication of tumors. Natural killer cells and T lymphocytes have a crucial role in tumor …

Nádorové onemocnění je druhou nejčastější příčinou úmrtí v České republice hned po
kardiovaskulárních chorobách. Nový vědní obor-nanomedicína, ukazuje slibný potenciál v …