Solutes unmask differences in clustering versus phase separation of FET proteins
M Kar, LT Vogel, G Chauhan, S Felekyan… - Nature …, 2024 - nature.com
Phase separation and percolation contribute to phase transitions of multivalent
macromolecules. Contributions of percolation are evident through the viscoelasticity of …
macromolecules. Contributions of percolation are evident through the viscoelasticity of …
Biomolecular phase separation through theoretical and computational microscope
R Kumar, DH Koo, YG Eom… - Bulletin of the Korean …, 2024 - Wiley Online Library
Biomolecular phase separation is a vital mechanism for orchestrating biomolecules within
living cells. This crucial role has spurred an intense pursuit to comprehend the molecular …
living cells. This crucial role has spurred an intense pursuit to comprehend the molecular …
Biomolecular Condensates Can Enhance Pathological RNA Clustering
Intracellular aggregation of repeat expanded RNA has been implicated in many
neurological disorders. Here, we study the role of biomolecular condensates on irreversible …
neurological disorders. Here, we study the role of biomolecular condensates on irreversible …
Microscopic model for aging of biocondensates
HL Roy, PDL Rios - arXiv preprint arXiv:2407.21710, 2024 - arxiv.org
Biomolecular condensates are membraneless compartments in the cell that are involved in
a wide diversity of biological processes. These phase-separated droplets usually exhibit a …
a wide diversity of biological processes. These phase-separated droplets usually exhibit a …
Backbone-mediated weakening of pairwise interactions enables percolation in mimics of protein condensates
Intrinsically disordered regions (IDRs) of proteins with specific sequence grammars can be
drivers of phase separation and percolation that enable the formation of biomolecular …
drivers of phase separation and percolation that enable the formation of biomolecular …
Hierarchical structural organization in bioinspired peptide coacervate microdroplets
This study explores the dynamic and hierarchical structural organization of peptide
coacervate microdroplets at the meso-to atomic-scale resolution using a combination of …
coacervate microdroplets at the meso-to atomic-scale resolution using a combination of …
Biomolecular condensates can enhance pathological RNA clustering
Intracellular aggregation of repeat expanded RNA has been implicated in many
neurological disorders. Here, we study the role of biomolecular condensates on irreversible …
neurological disorders. Here, we study the role of biomolecular condensates on irreversible …