Gap junctions consist of arrays of intercellular channels that enable adjacent cells to
communicate both electrically and metabolically. Gap junctions have a wide diversity of …

Connexins are assembled into dodecamer intercellular channels, a collection of which is
termed a gap junction, and their canonical function allowing direct exchange of ions and …

Connexin37-mediated regulation of cell cycle modulators and, consequently, growth arrest
lack mechanistic understanding. We previously showed that arterial shear stress up …

Prolonged population aging and unhealthy lifestyles contribute to the progressive
prevalence of arterial hypertension. This is accompanied by low-grade inflammation and …

Gap junctions (GJs), which are composed of connexins (Cxs), provide channels for direct
information exchange between cells. Cx expression has a strong spatial specificity; …

ABSTRACT Phosphorylation of connexin 43 (Cx43) is an important regulatory mechanism of
gap junction (GJ) function. Cx43 is modified by several kinases on over 15 sites within its∼ …

Gap junctions are specialized regions of the plasma membrane containing clusters of
channels that provide for the diffusion of ions and small molecules between adjacent cells. A …

Gap junctions mediate direct cell-to-cell communication by forming channels that physically
couple cells, thereby linking their cytoplasm, permitting the exchange of molecules, ions …

Necroptosis is known to play an important role in the pathophysiology of cerebral ischemia;
however, its role in the occurrence of secondary thalamic injury after focal cerebral infarction …

Ischemic events can culminate in acute myocardial infarction, which is generated by
irreversible cardiac lesions that cannot be restored due to the limited regenerative capacity …