Asthma is the commonest respiratory disease and one of unceasingly increasing prevalence
and burden. As such, asthma has attracted a major share or scientific interest and clinical …

Background Physical inactivity and high sedentary time are associated with adverse health
outcomes in several diseases. However, their impact in asthma is less clear. Objective We …

Background Physical inactivity and sedentary time are distinct behaviors that may be more
prevalent in severe asthma, contributing to poor disease outcomes. Physical activity and …

Identification of pathologic changes in early and mild obstructive lung disease has shown
the importance of the small airways and their contribution to symptoms. Indeed, significant …

Background Anti-T2 biological therapies have proven to effectively reduce acute
exacerbations and daily doses of oral steroids in severe eosinophilic asthma. Despite the …

Asthma is a chronic disease, affecting approximately 350 million people worldwide.
Inflammation and remodeling in asthma involve the large airways, and it is now widely …

Background Little is known about the role of small airway dysfunction (SAD) and its complex
relation with asthma control and physical activity (PA). Objective To investigate the …

Background Comprehensive studies investigated the role of T-cells in asthma which led to
personalised treatment options targeting severe eosinophilic asthma. However, little is …

Background In the year 2035, projections have estimated that 5% of the Scottish population
will be morbidly obese defined as a body mass index (BMI) greater than or equal to 40 kg/m …

Rationale Asthma, obesity and physical activity (PA) are interrelated. However, longitudinal
data with objective PA measures and direct assessment of body composition are still …