Hyperlipidemia is a major risk factor for cardiovascular morbidity and mortality. Statins are
the first-choice therapy for dyslipidemias and are considered the cornerstone of …

Statins are a cornerstone in the pharmacological prevention of cardiovascular disease.
Although generally well tolerated, a small subset of patients experience statin-related …

Rhabdomyolysis is a serious and potentially life threatening condition. Although consensus
criteria for rhabdomyolysis is lacking, a reasonable definition is elevation of serum creatine …

2014 BMA Medical Book Awards Highly Commended in Pathology category! Muscle Biopsy:
A Practical Approach gives you all of the unparalleled guidance necessary to effectively …

Rhabdomyolysis is characterized by severe acute muscle injury resulting in muscle pain,
weakness, and/or swelling with release of myofiber contents into the bloodstream …

Cholesterol-lowering statins effectively reduce the risk of major cardiovascular events.
Myopathy is the most important adverse effect, but its underlying mechanism remains …

Triacylglycerol (TAG) synthesis and storage in tissues such as adipose tissue and liver have
important roles in metabolic homeostasis. The molecular identification of genes encoding …

This 7th edition is a milestone in the series of Inborn Metabolic Diseases (IMD): Diagnosis
and Treatment, first published in 1990. Within the last 6 years a Copernican revolution in our …

Triacylglycerol (TAG) is the primary unit of energy storage in eukaryotic cells. TAG comprises
more than 90% of the content of white adipocytes, and TAG synthesis is essential in …

Exertional (exercise-induced) rhabdomyolysis is a potentially life threatening condition that
has been the subject of research, intense discussion, and media attention. The causes of …