The identification and cloning of the two major cannabinoid (CB1 and CB2) receptors
together with the discovery of their endogenous ligands in the late 80s and early 90s …

Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

This Technical Report was reaffirmed January 2024. This technical report updates the 2004
American Academy of Pediatrics technical report on the legalization of marijuana. Current …

The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …

Alzheimer's disease (AD) is the most common cause of dementia among older people.
There are no effective medications currently available to prevent and treat AD and halt …

Background: Cannabinoid has long been used for medicinal purposes. Cannabinoid
signaling has been considered the therapeutic target for treating pain, addiction, obesity …

Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays a crucial role catalysing the
hydrolysis of monoglycerides into glycerol and fatty acids. It links the endocannabinoid and …

Abstract Purpose of Review Cannabis has been used since ancient times for medical and
recreational research. This review article will document the validity of how medical cannabis …

Marijuana and aspirin have been used for millennia to treat a wide range of maladies
including pain and inflammation. Both cannabinoids, like marijuana, that exert anti …

Objective The use of cannabis as a therapeutic agent for various medical conditions has
been well documented. However, clinical trials in patients with Parkinson disease (PD) have …