Non-coding RNAs in hypertrophic scars and keloids: Current research and clinical relevance: A review

L Su, J Han - International Journal of Biological Macromolecules, 2024 - Elsevier
Hypertrophic scars (HS) and keloids (KD) are lesions that develop as a result of excessive
fibroblast proliferation and collagen deposition in response to dermal injury, leading to …

Can Electrical Stimulation Prevent Recurrence of Keloid Scars? A Scoping Review

RE George, CC Bay, SM Thornton… - Advances in Wound …, 2024 - liebertpub.com
Objective: Keloids represent a symptomatic, aberrant healing process that is difficult to treat
with high recurrence rates spanning from 55% to 100% if treated via excision without …

Efficacy and safety of sequential treatment with botulinum toxin type A, fractional CO2 laser, and topical growth factor for hypertrophic scar management: a …

J Wang, L Huang, J Li, R Xu, T Guo, T Huang, Y Wu… - Scientific Reports, 2024 - nature.com
Hypertrophic scars arise from aberrant wound healing and can lead to functional and
aesthetic impairments. One of the common interventions for treating hypertrophic scars is …

Revisiting roles of mast cells and neural cells in keloid: exploring their connection to disease activity

E Yeo, J Shim, SJ Oh, YH Choi, H Noh, H Kim… - Frontiers in …, 2024 - frontiersin.org
Background Mast cells (MCs) and neural cells (NCs) are important in a keloid
microenvironment. They might contribute to fibrosis and pain sensation within the keloid …

[HTML][HTML] Osteopathic approach for keloids and hypertrophic scars

B Bordoni, AR Escher, GT Girgenti, F Tobbi… - Cureus, 2023 - ncbi.nlm.nih.gov
The skin is a complex organ, a system that influences and is influenced by the body system,
with different skin layers always mechano-biologically active. In the presence of a lesion that …

[HTML][HTML] Exosomal microRNA-Based therapies for skin diseases

C Jibing, L Weiping, Y Yuwei, F Bingzheng… - Regenerative …, 2024 - Elsevier
Based on engineered cell/exosome technology and various skin-related animal models,
exosomal microRNA (miRNA)-based therapies derived from natural exosomes have shown …

Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis

L Yang, X Li, Y Wang - PeerJ, 2024 - peerj.com
Background Keloid is a chronic proliferative fibrotic disease caused by abnormal fibroblasts
proliferation and excessive extracellular matrix (ECM) production. Numerous fibrotic …

Dual-wavelength dye laser combined with betamethasone injection for treatment of keloids: protocol of a randomised controlled trial

J Wen, Z Li, W Liu, N Yu, X Wang - BMJ open, 2024 - bmjopen.bmj.com
Introduction Keloids, benign fibroproliferative tumours characterised by excessive fibroblast
proliferation and over-deposition of extracellular matrix, pose a therapeutic challenge with …

[HTML][HTML] Surgical scar management-an evaluation of surgical techniques

GA Căiţă, CF Lascu, FD Bodog, CL Buhaş… - Medicine and …, 2024 - ncbi.nlm.nih.gov
The purpose of this narrative review is to analyze surgical techniques for removing scar
tissue and minimizing them. A considerable proportion of the population have scars that are …

Laser-assisted corticoid delivery for the treatment of burn scars

S Menashe, L Heller, A Ofek, S Moscovici… - European Journal of …, 2025 - Springer
Background Non-fatal burns impact millions annually, are difficult to treat, and reduce quality
of life. Laser technology offers a promising approach for improving scar outcomes, in …