Tumors are not isolated entities, but complex systemic networks involving cell-cell
communication between transformed and non-transformed cells. The milieu created by …

Cancer stem cells (CSCs) represent a tumor subpopulation responsible for tumor metastasis
and resistance to chemo-and radiotherapy, ultimately leading to tumor relapse. As a …

Purpose: Glioblastoma (GBM) is the most common primary brain tumor. The identification of
blood biomarkers reflecting the tumor status represents a major unmet need for optimal …

Glioblastoma multiforme (GBM) are mortifying brain tumours that contain a subpopulation of
tumour cells with stem-like properties, termed glioblastoma stem-like cells (GSCs). GSCs …

Extracellular vesicles (EVs) mediate intercellular signaling and communication, allowing the
intercellular exchange of proteins, lipids, and genetic material. Their recognized role in the …

Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …

Glioblastoma is one of the most lethal human cancers, with poor survival despite surgery,
radiation treatment, and chemotherapy. Advances in the treatment of this type of brain tumor …

Glioblastomas (GBM) are highly aggressive primary brain tumors. Complex and dynamic
tumor microenvironment (TME) plays a crucial role in the sustained growth, proliferation, and …

Malignant gliomas are the most common and deadly type of central nervous system tumors.
Despite some advances in treatment, the mean survival time remains only about 1.25 years …

Abstract Significance: Secreted extracellular vesicles (EVs) are now considered veritable
entities for diagnosis, prognosis, and therapeutics. These structures are able to interact with …