Anomalous transport in the crowded world of biological cells

F Höfling, T Franosch - Reports on Progress in Physics, 2013 - iopscience.iop.org
A ubiquitous observation in cell biology is that the diffusive motion of macromolecules and
organelles is anomalous, and a description simply based on the conventional diffusion …

Heterogeneous anomalous transport in cellular and molecular biology

TA Waigh, N Korabel - Reports on Progress in Physics, 2023 - iopscience.iop.org
It is well established that a wide variety of phenomena in cellular and molecular biology
involve anomalous transport eg the statistics for the motility of cells and molecules are …

Anomalous diffusion models and their properties: non-stationarity, non-ergodicity, and ageing at the centenary of single particle tracking

R Metzler, JH Jeon, AG Cherstvy… - Physical Chemistry …, 2014 - pubs.rsc.org
Modern microscopic techniques following the stochastic motion of labelled tracer particles
have uncovered significant deviations from the laws of Brownian motion in a variety of …

Strange kinetics of single molecules in living cells

E Barkai, Y Garini, R Metzler - Physics today, 2012 - pubs.aip.org
For centuries, physical imaging tools have been opening new frontiers in biology. The
discovery of the cell nucleus by Scottish botanist Robert Brown was made possible by early …

In Vivo Anomalous Diffusion and Weak Ergodicity Breaking of Lipid Granules

JH Jeon, V Tejedor, S Burov, E Barkai… - Physical review …, 2011 - APS
Combining extensive single particle tracking microscopy data of endogenous lipid granules
in living fission yeast cells with analytical results we show evidence for anomalous diffusion …

A toolbox for determining subdiffusive mechanisms

Y Meroz, IM Sokolov - Physics Reports, 2015 - Elsevier
Subdiffusive processes have become a field of great interest in the last decades, due to
amounting experimental evidence of subdiffusive behavior in complex systems, and …

Intracellular transport of insulin granules is a subordinated random walk

SMA Tabei, S Burov, HY Kim… - Proceedings of the …, 2013 - National Acad Sciences
We quantitatively analyzed particle tracking data on insulin granules expressing fluorescent
fusion proteins in MIN6 cells to better understand the motions contributing to intracellular …

[HTML][HTML] Non-Brownian diffusion in lipid membranes: Experiments and simulations

R Metzler, JH Jeon, AG Cherstvy - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …

Single particle tracking in systems showing anomalous diffusion: the role of weak ergodicity breaking

S Burov, JH Jeon, R Metzler, E Barkai - Physical Chemistry Chemical …, 2011 - pubs.rsc.org
Anomalous diffusion has been widely observed by single particle tracking microscopy in
complex systems such as biological cells. The resulting time series are usually evaluated in …

Anomalous diffusion of phospholipids and cholesterols in a lipid bilayer and its origins

JH Jeon, HMS Monne, M Javanainen, R Metzler - Physical review letters, 2012 - APS
Combining extensive molecular dynamics simulations of lipid bilayer systems of varying
chemical compositions with single-trajectory analyses, we systematically elucidate the …