Mass spectrometry (MS) imaging links molecular information and the spatial distribution of
analytes within a sample. In contrast to most histochemical techniques, mass spectrometry …

Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

Biological tissues exhibit complex spatial heterogeneity that directs the functions of
multicellular organisms. Quantifying protein expression is essential for elucidating …

Metabolomics, along with other “omics” approaches, is rapidly becoming one of the major
approaches aimed at understanding the organization and dynamics of metabolic networks …

Retrospective proteomic studies, including those which aim to elucidate the molecular
mechanisms driving cancer, require the assembly and characterization of substantial patient …

MALDI imaging mass spectrometry is a highly sensitive and selective tool used to visualize
biomolecules in tissue. However, identification of detected proteins remains a difficult task …

Imaging mass spectrometry is increasingly used to identify new candidate biomarkers. This
clinical application of imaging mass spectrometry is highly multidisciplinary: expertise in …

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has
established itself among the plethora of mass spectrometry applications. In the biomedical …

Mass spectrometry imaging is a powerful tool for directly determining the distribution of
proteins, peptides, lipids, neurotransmitters, metabolites and drugs in neural tissue sections …

MALDI Mass Spectrometry Imaging has shown important potential for molecular
classification and pathology marker discovery. Protein markers identification is therefore of …