Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases
Key physiological functions of the liver, including glucose and lipid metabolism, become
disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated …
disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated …
Cancer, obesity, diabetes, and antidiabetic drugs: is the fog clearing?
The prevalence of obesity, of type 2 diabetes mellitus (T2DM), and of cancer are all
increasing globally. The relationships between these diseases are complex, and thus …
increasing globally. The relationships between these diseases are complex, and thus …
[HTML][HTML] Development and validation of an empirical dietary inflammatory index
Background: Knowledge on specific biological pathways mediating disease occurrence (eg,
inflammation) may be utilized to construct hypotheses-driven dietary patterns that take …
inflammation) may be utilized to construct hypotheses-driven dietary patterns that take …
Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science
Cancer is generally regarded as a localised disease, with the well-established role of the
tumour microenvironment. However, the realm of cancer goes beyond the tumour …
tumour microenvironment. However, the realm of cancer goes beyond the tumour …
Roles of adipokines in digestive diseases: markers of inflammation, metabolic alteration and disease progression
ML Chang, Z Yang, SS Yang - International journal of molecular sciences, 2020 - mdpi.com
Adipose tissue is a highly dynamic endocrine tissue and constitutes a central node in the
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …
interorgan crosstalk network through adipokines, which cause pleiotropic effects, including …
Colorectal cancers: an update on their molecular pathology
K Inamura - Cancers, 2018 - mdpi.com
Colorectal cancers (CRCs) are the third leading cause of cancer-related mortality worldwide.
Rather than being a single, uniform disease type, accumulating evidence suggests that …
Rather than being a single, uniform disease type, accumulating evidence suggests that …
Utility of inverse probability weighting in molecular pathological epidemiology
As one of causal inference methodologies, the inverse probability weighting (IPW) method
has been utilized to address confounding and account for missing data when subjects with …
has been utilized to address confounding and account for missing data when subjects with …
Adiponectin and intelectin-1: important adipokine players in obesity-related colorectal carcinogenesis
K Kawashima, K Maeda, C Saigo, Y Kito… - International journal of …, 2017 - mdpi.com
Overweight is believed to be associated with colorectal cancer risk. Adipose tissue is loose
connective tissue composed of adipocytes. It is now recognized as a major endocrine organ …
connective tissue composed of adipocytes. It is now recognized as a major endocrine organ …
Strain-level detection of Fusobacterium nucleatum in colorectal cancer specimens by targeting the CRISPR–Cas region
Y Shimomura, Y Sugi, A Kume, W Tanaka… - Microbiology …, 2023 - Am Soc Microbiol
Fusobacterium nucleatum is associated with colorectal cancer (CRC), and identical F.
nucleatum strains seemed to be detected in 75% of patients who exhibited the presence of …
nucleatum strains seemed to be detected in 75% of patients who exhibited the presence of …
Metabolomic signatures of inflammation and metabolic dysregulation in relation to colorectal cancer risk
Background Inflammation and metabolic dysregulation are associated with increased risk of
colorectal cancer (CRC); the underlying mechanisms are not fully understood. We …
colorectal cancer (CRC); the underlying mechanisms are not fully understood. We …