Radiation‐induced cardiovascular disease: review of an underrecognized pathology

E Belzile‐Dugas, MJ Eisenberg - Journal of the American Heart …, 2021 - Am Heart Assoc
Radiation therapy demonstrates a clear survival benefit in the treatment of several
malignancies. However, cancer survivors can develop a wide array of cardiotoxic …

Radiotherapy toxicity

D De Ruysscher, G Niedermann, NG Burnet… - Nature Reviews …, 2019 - nature.com
Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

Tumor microenvironment as a “game changer” in cancer radiotherapy

M Jarosz-Biej, R Smolarczyk, T Cichoń… - International journal of …, 2019 - mdpi.com
Radiotherapy (RT), besides cancer cells, also affects the tumor microenvironment (TME):
tumor blood vessels and cells of the immune system. It damages endothelial cells and …

Association of left anterior descending coronary artery radiation dose with major adverse cardiac events and mortality in patients with non–small cell lung cancer

KM Atkins, TL Chaunzwa, N Lamba… - JAMA …, 2021 - jamanetwork.com
Importance Radiotherapy accelerates coronary heart disease (CHD), but the dose to critical
cardiac substructures has not been systematically studied in lung cancer. Objective To …

Vascular toxic effects of cancer therapies

J Herrmann - Nature Reviews Cardiology, 2020 - nature.com
Cancer therapies can lead to a broad spectrum of cardiovascular complications. Among
these, cardiotoxicities remain of prime concern, but vascular toxicities have emerged as the …

Mechanisms of radiation-induced endothelium damage: Emerging models and technologies

H Wijerathne, JC Langston, Q Yang, S Sun… - Radiotherapy and …, 2021 - Elsevier
Radiation-induced endothelial/vascular injury is a major complicating factor in radiotherapy
and a leading cause of morbidity and mortality in nuclear or radiological catastrophes …

X-ray-based techniques to study the nano–bio interface

C Sanchez-Cano, RA Alvarez-Puebla, JM Abendroth… - ACS …, 2021 - ACS Publications
X-ray-based analytics are routinely applied in many fields, including physics, chemistry,
materials science, and engineering. The full potential of such techniques in the life sciences …

Endothelial dysfunction as a complication of anti-cancer therapy

JD Terwoord, AM Beyer, DD Gutterman - Pharmacology & therapeutics, 2022 - Elsevier
Recent strides in anti-cancer therapeutics have improved longevity and led to a growing
population of cancer survivors, who are increasingly likely to die of other causes. Treatment …

The cognitive effects of radiotherapy for brain metastases

EJ Lehrer, BM Jones, DR Dickstein, S Green… - Frontiers in …, 2022 - frontiersin.org
Brain metastases are the most common intracranial neoplasm and are seen in upwards of
10-30% of patients with cancer. For decades, whole brain radiation therapy (WBRT) was the …

Mechanisms and review of clinical evidence of variations in relative biological effectiveness in proton therapy

H Paganetti - International Journal of Radiation Oncology* Biology …, 2022 - Elsevier
Proton therapy is increasingly being used as a radiation therapy modality. There is
uncertainty about the biological effectiveness of protons relative to photon therapies as it …