Astrocytic and microglial cells as the modulators of neuroinflammation in Alzheimer's disease

D Singh - Journal of neuroinflammation, 2022 - Springer
Neuroinflammation is instigated by the misfiring of immune cells in the central nervous
system (CNS) involving microglia and astrocytes as key cell-types. Neuroinflammation is a …

Neuro-inflammation and anti-inflammatory treatment options for Alzheimer's disease

T Ozben, S Ozben - Clinical biochemistry, 2019 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss and dementia. The pathological characteristics of AD include the deposition of …

Mental health and periodontal and peri‐implant diseases

J Ball, I Darby - Periodontology 2000, 2022 - Wiley Online Library
Mental health disorders, particularly depression and anxiety, affect a significant number of
the global population. Several pathophysiological pathways for these disorders have been …

Bacteroides Fragilis in the gut microbiomes of Alzheimer's disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice

Y Xia, Y Xiao, ZH Wang, X Liu, AM Alam… - Nature …, 2023 - nature.com
Gut dysbiosis contributes to Alzheimer's disease (AD) pathogenesis, and Bacteroides strains
are selectively elevated in AD gut microbiota. However, it remains unknown which …

Comprehensive review of mechanisms of pathogenesis involved in Alzheimer's disease and potential therapeutic strategies

P Sharma, P Srivastava, A Seth, PN Tripathi… - Progress in …, 2019 - Elsevier
AD is a progressive neurodegenerative disorder and a leading cause of dementia in an
aging population worldwide. The enormous challenge which AD possesses to global …

Microglial priming in neurodegenerative disease

VH Perry, C Holmes - Nature Reviews Neurology, 2014 - nature.com
Under physiological conditions, the number and function of microglia—the resident
macrophages of the CNS—is tightly controlled by the local microenvironment. In response to …

Molecular mechanisms of neuroinflammation in aging and Alzheimer's disease progression

FL Andronie-Cioara, AI Ardelean… - International journal of …, 2023 - mdpi.com
Aging is the most prominent risk factor for late-onset Alzheimer's disease. Aging associates
with a chronic inflammatory state both in the periphery and in the central nervous system, the …

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease

MR Minter, JM Taylor, PJ Crack - Journal of neurochemistry, 2016 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most
common cause of dementia. Deposition of amyloid‐β (Aβ) remains a hallmark feature of the …

Myocardial inflammation predicts remodeling and neuroinflammation after myocardial infarction

JT Thackeray, HC Hupe, Y Wang, JP Bankstahl… - Journal of the American …, 2018 - jacc.org
Background: The local inflammatory tissue response after acute myocardial infarction (MI)
determines subsequent healing. Systemic interaction may induce neuroinflammation as a …

[HTML][HTML] The effect of curcumin on cognition in Alzheimer's disease and healthy aging: A systematic review of pre-clinical and clinical studies

SD Voulgaropoulou, T Van Amelsvoort, J Prickaerts… - Brain research, 2019 - Elsevier
Alzheimer's disease constitutes a growing cause of cognitive impairment in aging
population. Given that current treatments do not produce the desired therapeutic effects, the …