Human longevity is a complex phenotype resulting from the combinations of context-
dependent gene-environment interactions that require analysis as a dynamic process in a …

Both genomics-and proteomics-based investigations have identified several essential
genes, proteins, and pathways that may facilitate human adaptive genotype/phenotype in a …

Over millions of years, vertebrate species populated vast environments spanning the globe.
Among the most challenging habitats encountered were those with limited availability of …

Simple Summary The yak is a multipurpose domesticated animal that serves as a protein
source for local herders and a sacred carrier of culture and religion. Besides their economic …

Background: Tibetans have lived at very high altitudes for thousands of years, and have a
distinctive suite of physiological traits that enable them to tolerate environmental hypoxia …

Archeologically attested human occupation on the Tibetan Plateau (TP) can be traced back
to 160 thousand years ago (kya) via the archaic Xiahe people and 30∼ 40 kya via the Nwya …

Archaeological, genetic, and linguistic evidence has supported the idea that northern China
is the original center of modern Sino‐Tibetan‐speaking populations. However, the …

High‐altitude areas are important socio‐economical habitats with ruminants serving as a
major source of food and commodities for humans. Living at high altitude, however, is …

Human oral microbes play a vital role maintaining host metabolic homeostasis. The Qinghai-
Tibet Plateau is mainly characterized by a high altitude, dry, cold, and hypoxic environment …

Great progress has been made over recent years in the identification of selection signatures
in the genomes of livestock species. This work has primarily been carried out in commercial …