Sleep disorders

MK Pavlova, V Latreille - The American journal of medicine, 2019 - Elsevier
Sleep disorders are frequent and can have serious consequences on patients' health and
quality of life. While some sleep disorders are more challenging to treat, most can be easily …

Obstructive sleep apnea, depression and cognitive impairment

J Vanek, J Prasko, S Genzor, M Ociskova, K Kantor… - Sleep medicine, 2020 - Elsevier
Objective Obstructive sleep apnea (OSA) is a severe disorder with a high prevalence.
Psychiatric comorbidities, especially depressive symptoms and cognitive dysfunction, are …

Hypoxia-inducible factors and obstructive sleep apnea

NR Prabhakar, YJ Peng… - The Journal of clinical …, 2020 - Am Soc Clin Investig
Intermittent hypoxia (IH) is a hallmark manifestation of obstructive sleep apnea (OSA), a
widespread disorder of breathing. This Review focuses on the role of hypoxia-inducible …

The relationship between inflammation and neurocognitive dysfunction in obstructive sleep apnea syndrome

X Liu, Y Ma, R Ouyang, Z Zeng, Z Zhan, H Lu… - Journal of …, 2020 - Springer
Obstructive sleep apnea syndrome (OSAS), a state of sleep disorder, is characterized by
repetitive apnea, chronic hypoxia, oxygen desaturation, and hypercapnia. Previous studies …

[HTML][HTML] Los trastornos del sueño y su compleja relación con las funciones cognitivas

D Lira, N Custodio - Revista de Neuro-Psiquiatría, 2018 - scielo.org.pe
El sueño es una necesidad fisiológica que juega múltiples roles en los seres humanos y
presenta características especiales que van variando con la edad y el medio ambiente. Es …

Pitolisant for residual excessive daytime sleepiness in OSA patients adhering to CPAP: a randomized trial

JL Pépin, O Georgiev, R Tiholov, V Attali… - Chest, 2021 - Elsevier
Background Excessive daytime sleepiness (EDS) in individuals with OSA syndrome
persisting despite good adherence to CPAP is a disabling condition. Pitolisant is a selective …

Pitolisant for daytime sleepiness in patients with obstructive sleep apnea who refuse continuous positive airway pressure treatment. A randomized trial

Y Dauvilliers, J Verbraecken, M Partinen… - American Journal of …, 2020 - atsjournals.org
Rationale: Excessive daytime sleepiness is a common disabling symptom in obstructive
sleep apnea syndrome. Objectives: To evaluate the efficacy and safety of pitolisant, a …

Gender-specific association between obstructive sleep apnea and cognitive impairment among adults

K Qiu, M Mao, Y Hu, X Yi, Y Zheng, Z Ying, D Cheng… - Sleep Medicine, 2022 - Elsevier
Objectives This study aims to explore the gender-specific association between obstructive
sleep apnea (OSA) and cognitive impairment. Methods Participants from UK biobank who …

Obstructive sleep apnea: cognitive outcomes

A Patel, DJ Chong - Clinics in geriatric medicine, 2021 - geriatric.theclinics.com
Cognition includes many domains of brain function, such as language, planning, problem
solving, processing speed, various memory types, visuospatial function, attention …

Cognitive effects of treating obstructive sleep apnea: a meta-analysis of randomized controlled trials

ML Wang, C Wang, M Tuo, Y Yu… - Journal of …, 2020 - content.iospress.com
Background: Obstructive sleep apnea (OSA) is associated with cognitive impairment and
increased risks of dementia. However, the effect of continuous positive airway pressure …