Heterotrimeric G protein-coupled receptors (GPCRs) comprise the largest receptor family in
mammals and are responsible for the regulation of most physiological functions. Besides …

Our sense of taste arises from the sensory information generated after compounds in the
oral cavity and oropharynx activate taste receptor cells situated on taste buds. This produces …

Background The human taste experience is the result of five basic taste qualities, namely
sweet, salty, bitter, sour and umami. Sweet, bitter, and umami are mediated by G protein …

The current understanding of peripheral molecular events involved in sweet taste sensation
in humans is reviewed. Included are discussions of the sweetener receptor T1R2/T1R3, its …

In the upper respiratory epithelium, bitter and sweet taste receptors present in solitary
chemosensory cells influence antimicrobial innate immune defense responses. Whereas …

Prior research has explored modifying taste through electrical stimulation. While promising,
such interfaces often only elicit taste changes while in contact with the user's tongue (eg …

Owing to the public health concern associated with the consumption of added sugar, the
World Health Organization recommends cutting down sugar in processed foods …

Aim This work studies the development and evaluation of Gymnema sylvestre (GYM) extract
loaded sustained release polymeric nanoparticles (PNPs) for enhanced bioavailability and …

Sucrose provides both sweetness and energy by binding to both Venus flytrap domains
(VFD) of the heterodimeric sweet taste receptor (T1R2/T1R3). In contrast, non-caloric …

Bitter and sweet taste G protein-coupled receptors (known as T2Rs and T1Rs, respectively)
were originally identified in type II taste cells on the tongue, where they signal perception of …