Microvesicles represent a newly identified mechanism of intercellular communication. Two
different types of microvesicles have been identified: membrane-derived vesicles (EVs) and …

Cutaneous wound repair is a highly coordinated cascade of cellular responses to injury
which restores the epidermal integrity and its barrier functions. Even under optimal healing …

Mesenchymal stem cells (MSCs) are currently being widely investigated both in the lab and
in clinical trials for multiple disease states. The differentiation, trophic, and …

Executive summary In this Commission, we argue that a combination of poor quality science,
unclear funding models, unrealistic hopes, and unscrupulous private clinics threatens …

Mesenchymal stromal cells (MSCs) harbor great therapeutic potential for numerous
diseases. From early clinical trials, success and failure analysis, bench-to-bedside and back …

Rupture of the anterior cruciate ligament (ACL) is one of the most common ligamentous
injuries of the knee. Limitations of allografts and autografts in ACL reconstruction as well as …

Significance: Cutaneous wound healing is a serious problem worldwide that affects patients
with various wound types, resulting from burns, traumatic injuries, and diabetes. Despite the …

We demonstrate a straightforward method to encapsulate siRNA into naturally available and
unmodified human apoferritin. The encapsulation into apoferritin is independent of the …

Malignant pleural mesothelioma is a rare but devastating cancer of the pleural lining with no
effective treatment. The tumour is often diffusely spread throughout the chest cavity, making …

The treatment of autoimmune diseases still poses a major challenge, frequently relying on
non-specific immunosuppressive drugs. Current efforts aim at reestablishing self tolerance …