OBJECTIVE: To examine the relationships between clinical or histological chorioamnionitis
and cerebral palsy using a meta-analysis approach. DATA SOURCES: A systematic review …

The mechanisms involved in human pregnancy maintenance and parturition are highly
complex and involve mother, fetus and placenta. The “final common pathway” to delivery is …

Purpose Prostaglandins play a critical role in cervical ripening by increasing inflammatory
mediators in the cervix and inducing cervical remodeling. Prostaglandin E1 (PGE1) and …

Oxytocin, a hormone involved in numerous physiologic processes, plays a central role in the
mechanisms of parturition and lactation. It acts through its receptor, which belongs to the G …

The gestational period is an incredibly stressful time for a pregnant woman. Pregnant
patients constantly seek effective and reliable compounds in order to achieve a healthy …

Preterm birth (PTB) is the leading cause of infant death and disability worldwide. The onset
of preterm uterine contractions is preceded by asymptomatic cervical remodelling and …

At the end of gestation, the cervical tissue changes profoundly. As a result of these changes,
the uterine cervix becomes soft and vulnerable to dilation. The process occurring in the …

Preterm birth (PTB; spontaneous delivery prior to 37 weeks gestation) affects one out of
eight infants born in the United States and is the most common cause of neonatal morbidity …

In recent years evidence has been accumulated showing that miRNAs can act as potential
biomarkers or targets for therapy of preterm birth, one of the most important problems in …

Neutrophils are surveillance cells, and the first to react and migrate to sites of inflammation
and infection following a chemotactic gradient. Neutrophils play a key role in both sterile …