Negative regulation of growth hormone receptor signaling

A Flores-Morales, CJ Greenhalgh… - Molecular …, 2006 - academic.oup.com
GH has been of significant scientific interest for decades because of its capacity to
dramatically change physiological growth parameters. Furthermore, GH interacts with a …

Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network

D Redelman, LA Welniak, D Taub, WJ Murphy - Cellular immunology, 2008 - Elsevier
Neuroendocrine hormones such as growth hormone (GH) and prolactin (PRL) have been
demonstrated to accelerate the recovery of the immune response after chemotherapy and …

Attenuation of CXCR4 responses by CCL18 in acute lymphocytic leukemia B cells

J Catusse, S Wollner, M Leick… - Journal of cellular …, 2010 - Wiley Online Library
CCL18 and CXCL12 are homeostatic chemokines with high constitutive concentrations in
serum. Elevated levels of CCL18 have been described in various diseases including …

Suppressors of cytokine signaling (SOCS) 1 and SOCS3 interact with and modulate fibroblast growth factor receptor signaling

T Ben-Zvi, A Yayon, A Gertler… - Journal of cell …, 2006 - journals.biologists.com
Fibroblast growth factor receptor (FGFR) signaling is transduced by the mitogen-activated
protein kinase (MAPK) cascade and the signal transducers and activators of transcription …

SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis

Y Le, BM Zhu, B Harley, SY Park, T Kobayashi… - Immunity, 2007 - cell.com
The chemokine CXCL12 induces prolonged focal adhesion kinase (FAK) phosphorylation
and sustained proadhesive responses in progenitor bone-marrow (BM) B cells, but not in …

Expression of the growth hormone/insulin-like growth factor axis during Balb/c thymus ontogeny and effects of growth hormone upon ex vivo T cell differentiation

H Kermani, L Goffinet, M Mottet, G Bodart… - …, 2012 - karger.com
Aims: We address the question of the expression and the role of the growth hormone/insulin-
like growth factor (GH/IGF) axis in the thymus. Methods: Using RT-qPCR, the expression …

CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression

NJ Stevenson, MR Addley, EJ Ryan… - Journal of Leucocyte …, 2009 - academic.oup.com
The chemokine eotaxin/CCL11 is an important mediator of leukocyte migration, but its effect
on inflammatory cytokine signaling has not been explored. In this study, we find that CCL11 …

[HTML][HTML] CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis

T Takekoshi, X Wu, H Mitsui, Y Tada, MC Kao… - Journal of Investigative …, 2013 - Elsevier
CXCR4 is expressed by basal keratinocytes (KCs), but little is known about its function in
inflamed skin. We crossed K14-Cre and CXCR4 flox/flox (f/f) transgenic mice, resulting in …

Toll-like receptor 3 and suppressor of cytokine signaling proteins regulate CXCR4 and CXCR7 expression in bone marrow-derived human multipotent stromal cells

SL Tomchuck, SL Henkle, SB Coffelt, AM Betancourt - PloS one, 2012 - journals.plos.org
Background The use of bone marrow-derived human multipotent stromal cells (hMSC) in
cell-based therapies has dramatically increased in recent years, as researchers have …

Reciprocal role of SIRT6 and Hexokinase 2 in the regulation of autophagy driven monocyte differentiation

A Singh, E Sen - Experimental Cell Research, 2017 - Elsevier
Emerging evidences suggest the impact of autophagy on differentiation but the underlying
molecular links between metabolic restructuring and autophagy during monocyte …