Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms
Cryogenic electron tomography (cryo-ET) visualizes the 3D spatial distribution of
macromolecules at nanometer resolution inside native cells. However, automated …
macromolecules at nanometer resolution inside native cells. However, automated …
[PDF][PDF] On bias, variance, overfitting, gold standard and consensus in single-particle analysis by cryo-electron microscopy
COS Sorzano, A Jiménez-Moreno… - … Section D: Structural …, 2022 - journals.iucr.org
Cryo-electron microscopy (cryoEM) has become a well established technique to elucidate
the 3D structures of biological macromolecules. Projection images from thousands of …
the 3D structures of biological macromolecules. Projection images from thousands of …
MemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomography
L Lamm, S Zufferey, RD Righetto, W Wietrzynski… - bioRxiv, 2024 - biorxiv.org
MemBrain v2 is a deep learning-enabled program aimed at the efficient analysis of
membranes in cryo-electron tomography (cryo-ET). The final v2 release of MemBrain will …
membranes in cryo-electron tomography (cryo-ET). The final v2 release of MemBrain will …
Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM
Electron crystallography can reveal the structure of membrane proteins within 2D crystals
under close-to-native conditions. High-resolution structural information can only be reached …
under close-to-native conditions. High-resolution structural information can only be reached …
[HTML][HTML] CryoEM: a crystals to single particles round-trip
H Hebert - Current opinion in structural biology, 2019 - Elsevier
Highlights•Electron crystallography from 2D-or thin 3D crystals may provide structural
information which is difficult to obtain with other methods.•3D maps are related to the …
information which is difficult to obtain with other methods.•3D maps are related to the …
Detecting all possible ionospheric precursors by kernel-based two-dimensional principal component analysis
JW Lin, JS Chiou, CT Chao - IEEE Access, 2019 - ieeexplore.ieee.org
Kernel-based two-dimensional principal component analysis (K2DPCA), a nonlinear
method, was performed to examine ionospheric 2-D total electron content (TEC) variations …
method, was performed to examine ionospheric 2-D total electron content (TEC) variations …
Single particle analysis for high-resolution 2D electron crystallography
R Righetto, H Stahlberg - cryoEM: Methods and Protocols, 2021 - Springer
Electron crystallography has been used for decades to determine three-dimensional
structures of membrane proteins embedded in a lipid bilayer. However, high-resolution …
structures of membrane proteins embedded in a lipid bilayer. However, high-resolution …
[PDF][PDF] Retrieving High-Resolution Information from Disordered 2D Crystals by Single Particle Cryo-EM
H Stahlberg - researchgate.net
Electron crystallography can reveal the structure of membrane proteins within 2D crystals
under close-to-native conditions. High-resolution structural information can only be reached …
under close-to-native conditions. High-resolution structural information can only be reached …
[图书][B] A Journey towards Understanding Biology Holistically at the Nanoscale
TH Moser - 2018 - search.proquest.com
Characterizing biological processes with microscopy techniques that allow one to directly
visualize the complexity of life is an important component of understanding both …
visualize the complexity of life is an important component of understanding both …