Mitochondria have a central role in regulating a range of cellular activities and host
responses upon bacterial infection. Multiple pathogens affect mitochondria dynamics and …

Cardiovascular disease (CVD) accounts for almost half of all deaths related to non-
communicable disease worldwide, making it the single largest global cause of mortality …

Metabolism is a major regulator of immune cell function, but it remains difficult to study the
metabolic status of individual cells. Here, we present Compass, an algorithm to characterize …

Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, is a
chronic relapsing inflammatory disease of the gastrointestinal tract that closely related to …

Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which
primarily infects the macrophages. Nearly a quarter of the world's population is infected …

In the lungs, fibrosis is a growing clinical problem that results in shortness of breath and can
end up in respiratory failure. Even though the main fibrotic disease affecting the lung is …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) remains as a leading killer
among infectious diseases worldwide. The nature of the host immune response dictates …

Macrophages play an integral role in host defenses against intracellular bacterial
pathogens. A remarkable plasticity allows for adaptation to the needs of the host to …

While the existence of a special relationship between Mycobacterium tuberculosis (Mtb) and
host lipids has long been known, it remains a challenging enigma. It was clearly established …

Globally, an estimated 107 million people have an alcohol use disorder (AUD) leading to 2.8
million premature deaths each year. Tuberculosis (TB) is one of the leading causes of death …