[HTML][HTML] Pluripotent stem cell-based cell therapy—promise and challenges

S Yamanaka - Cell stem cell, 2020 - cell.com
Human pluripotent stem cells such as embryonic stem cells (ESCs) and induced pluripotent
stem cells (iPSCs) provide unprecedented opportunities for cell therapies against intractable …

Direct cell reprogramming: approaches, mechanisms and progress

H Wang, Y Yang, J Liu, L Qian - Nature Reviews Molecular Cell Biology, 2021 - nature.com
The reprogramming of somatic cells with defined factors, which converts cells from one
lineage into cells of another, has greatly reshaped our traditional views on cell identity and …

[HTML][HTML] Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

W Wei, H Dai - Bioactive materials, 2021 - Elsevier
In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

A Nourian Dehkordi, F Mirahmadi Babaheydari… - Stem cell research & …, 2019 - Springer
Normal wound healing is a dynamic and complex multiple phase process involving
coordinated interactions between growth factors, cytokines, chemokines, and various cells …

Induced pluripotent stem cell technology: a decade of progress

Y Shi, H Inoue, JC Wu, S Yamanaka - Nature reviews Drug discovery, 2017 - nature.com
Since the advent of induced pluripotent stem cell (iPSC) technology a decade ago,
enormous progress has been made in stem cell biology and regenerative medicine. Human …

3-D bioprinting technologies in tissue engineering and regenerative medicine: Current and future trends

ES Bishop, S Mostafa, M Pakvasa, HH Luu, MJ Lee… - Genes & diseases, 2017 - Elsevier
Advances in three-dimensional (3D) printing have increased feasibility towards the
synthesis of living tissues. Known as 3D bioprinting, this technology involves the precise …

[HTML][HTML] Transcriptional addiction in cancer

JE Bradner, D Hnisz, RA Young - Cell, 2017 - cell.com
Cancer arises from genetic alterations that invariably lead to dysregulated transcriptional
programs. These dysregulated programs can cause cancer cells to become highly …

Bioprinting 3D microfibrous scaffolds for engineering endothelialized myocardium and heart-on-a-chip

YS Zhang, A Arneri, S Bersini, SR Shin, K Zhu… - Biomaterials, 2016 - Elsevier
Engineering cardiac tissues and organ models remains a great challenge due to the
hierarchical structure of the native myocardium. The need of integrating blood vessels brings …

Gelatin methacrylate (GelMA)-based hydrogels for cell transplantation: an effective strategy for tissue engineering

S Xiao, T Zhao, J Wang, C Wang, J Du, L Ying… - Stem cell reviews and …, 2019 - Springer
Gelatin methacrylate (GelMA)-based hydrogels are gaining a great deal of attention as
potentially implantable materials in tissue engineering applications because of their …

A decade of transcription factor-mediated reprogramming to pluripotency

K Takahashi, S Yamanaka - Nature reviews Molecular cell biology, 2016 - nature.com
The past 10 years have seen great advances in our ability to manipulate cell fate, including
the induction of pluripotency in vitro to generate induced pluripotent stem cells (iPSCs). This …