Introduction: Spirooxindole, a unique and versatile scaffold, has been widely studied in
some fields such as pharmaceutical chemistry and synthetic chemistry. Especially in the …

Oxindole derivatives are known for their great interest in the field of Medicinal Chemistry, as
they display vast biological activities. Recent efforts concerning the preparation of oxindole …

The present study was purported to assess the toxicological profile of bare and polyethylene
glycol (PEG) coated spherical silver nanoparticles (AgNPs) by means of in vitro (on human …

A series of diaryl ethers were synthesized and their human (h) carbonic anhydrase (CA)
isoenzymes hCA I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE) …

Multicomponent reactions (MCRs) are a valuable tool in diversity‐oriented synthesis. Its
application to privileged structures is gaining relevance in the fields of organic and …

Herein, we reported a novel strategy for the fabrication of bifunctional metal–organic
framework based nanozymes (oxidized UiO-66-NH 2@ Ce), which displayed excellent …

Isatin has been used in design and synthesis of diverse types of heterocyclic and
carbocyclic compounds and considered as a valuable building block in organic synthesis …

An efficient catalyst-free procedure is reported for the one-pot three-component synthesis of
novel spiro-benzoxazole derivatives via the condensation reaction of isatins …

The solvents used in chemistry are a fundamental element of the environmental
performance of processes in corporate and academic laboratories. Their influence on costs …

PEG-400 has been used as a green and biodegradable polymeric solvent for the one-pot,
two-step, multi-component synthesis of novel asymmetrical bis-spirooxindole derivatives by …