Biological markers for depression are of great interest to aid in elucidating the causes of
major depression. We assess currently available biological markers to query their validity for …

The cost of psychiatric illness to the UK economy was recently estimated at£ 77 billion
annually. Despite years of research no firm aetiological explanation exists, and with no …

BackgroundThe role of folate, vitamin B12 and homocysteine levels in depression is not
clear. AimsTo investigate cross-sectional and prospective associations between folate, B12 …

INTRODUÇÃO: A vitamina B12 é hidrossolúvel, não-sintetizada pelo organismo humano,
presente em alimentos de origem animal. Sua deficiência é muito freqüente entre idosos …

Methylmalonic acid (MMA) as a functional marker of vitamin B12 deficiency has attracted
extensive attention. However, the highly selective and sensitive detection of MMA in a …

Background: Bipolar disorder (BD) is a psychiatric disorder with an uncertain aetiology.
Recently, special attention has been given to homocysteine (Hcy), as it has been suggested …

Background Higher homocysteine (Hcy) level has been suggested to be associated with
major psychiatric disorders (MPDs), such as schizophrenia (SCZ), bipolar disorder (BD), and …

Schizophrenia (SZ) is a debilitating and heterogeneous disease. We hypothesized that the
oxytocin (OXT) system, inflammation and one-carbon metabolism would have a link with SZ …

The term'one-carbon metabolism'is commonly used to describe 3 separate metabolic
processes: folate metabolism, the homocysteine remethylation cycle, and the …

Sole measurement of plasma vitamin B12 is no longer enough to identify vitamin B12 (B12)
deficiency. When plasma vitamin B12 is in the low-normal range, especially between 201 …