One of the brain sites more directly related with learning and memory processes is the
hippocampus. We recorded, in conscious mice, the activity-dependent changes taking place …

Brain ischemia induces neuronal loss which is caused in part by excitotoxicity and free
radical formation. Here, we report that mangiferin and morin, two antioxidant polyphenols …

Contemporary neuroscientists are paying increasing attention to subcellular, molecular and
electrophysiological mechanisms underlying learning and memory processes. Recent …

Associative learning depends on multiple cortical and subcortical structures, including
striatum, hippocampus, and amygdala. Both glutamatergic and dopaminergic …

Activity‐dependent changes taking place at the hippocampal perforant pathway–dentate
gyrus synapse during classical eyeblink conditioning were recorded in adult …

Previous in vitro studies have characterized the electrophysiological properties and
molecular events associated with long-term potentiation (LTP), but as yet there are no in vivo …

Adult heterozygous Lurcher mice show a degeneration of almost all Purkinje cells and 90%
of the granular cells of the cerebellum, resulting in ataxia or general deficits in motor …

A leading candidate in the process of memory formation is hippocampal long-term
potentiation (LTP), a persistent enhancement in synaptic strength evoked by the repetitive …

Wild-type and single-transgenic (APP, PS1) and double-transgenic (APP+ PS1) mice were
studied at three different (3-, 12-, and 18-month-old) age periods. Transgenic mice had …

The hippocampal CA3-CA1 synapse is an excellent experimental model for studying the
interactions between short-and long-term plastic changes taking place following high …