Nanozyme-modified metal–organic frameworks with multienzymes activity as biomimetic catalysts and electrocatalytic interfaces

P Ling, S Cheng, N Chen, C Qian… - ACS applied materials & …, 2020 - ACS Publications
Many metal–organic frameworks have been designed and synthesized for biosensors
because of high surface area and porosity, suitable size, and good biocompatibility. Despite …

AI-powered simulation-based inference of a genuinely spatial-stochastic gene regulation model of early mouse embryogenesis

MA Ramirez Sierra, TR Sokolowski - PLOS Computational Biology, 2024 - journals.plos.org
Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a
central challenge in developmental biology, particularly in early mammalian development …

Waves in a stochastic cell motility model

C Hamster, P van Heijster - Bulletin of Mathematical Biology, 2023 - Springer
Abstract In Bhattacharya et al.(Sci Adv 6 (32): 7682, 2020), a set of chemical reactions
involved in the dynamics of actin waves in cells was studied at two levels. The microscopic …

Modeling and simulation of Lac-Operon using reaction-diffusion master equation on heterogeneous parallel platforms

NG Bhat, S Balaji - Computer Physics Communications, 2024 - Elsevier
Abstract The Lac-Operon is a pivotal molecular mechanism controlling gene expression in
response to presence or absence of lactose. Mastering its dynamics aids cellular …

AI-powered simulation-based inference of a genuinely spatial-stochastic model of early mouse embryogenesis

MA Ramirez-Sierra, TR Sokolowski - arXiv preprint arXiv:2402.15330, 2024 - arxiv.org
Understanding how multicellular organisms reliably orchestrate cell-fate decisions is a
central challenge in developmental biology. This is particularly intriguing in early …

[PDF][PDF] Generic importance sampling via stochastic optimal control and dimensionality reduction for stochastic reaction networks

SF Münker - 2024 - publications.rwth-aachen.de
Abstract A Stochastic Reaction Network (SRN) is a stochastic process applied to model
many real-life phenomena, including the time evolution of biological and chemical systems …

Stochastic Spatiotemporal Simulation of a General Reaction System

AJ Loza, MS Sherman - bioRxiv, 2022 - biorxiv.org
Biological systems frequently contain biochemical species present as small numbers of
slowly diffusing molecules, leading to fluctuations that invalidate deterministic analyses of …

Particle-based methods for mesoscopic transport processes

Z Li, W Pan, AM Tartakovsky - Handbook of Materials Modeling …, 2020 - Springer
Biological phenomena at cellular and subcellular levels involve transport of reacting
biochemical species, including proteins, enzymes, and nutrients. At the mesoscopic scale …

[图书][B] Model-Guided Design of RNA-Based Synthetic Circuits for the Dynamic Regulation of Gene Expression

JR Ryan - 2022 - search.proquest.com
A longstanding goal in synthetic biology has been to build synthetic gene circuits with the
ability to harness nature's capability of precise gene expression regulation. Advancements …

Introducing Parameter Clustering to the OED Procedure for Model Calibration of a Synthetic Inducible Promoter in S. cerevisiae

Z Hou - Processes, 2021 - mdpi.com
In recent years, synthetic gene circuits for adding new cell features have become one of the
most powerful tools in biological and pharmaceutical research and development. However …