Cellular and molecular mechanisms of skin wound healing

OA Peña, P Martin - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Wound healing is a complex process that involves the coordinated actions of many different
tissues and cell lineages. It requires tight orchestration of cell migration, proliferation, matrix …

Immune-epithelial cross talk in regeneration and repair

L Guenin-Mace, P Konieczny… - Annual review of …, 2023 - annualreviews.org
The epithelial tissues that line our body, such as the skin and gut, have remarkable
regenerative prowess and continually renew throughout our lifetimes. Owing to their barrier …

Unraveling therapeutic opportunities and the diagnostic potential of microRNAs for human lung cancer

O Sweef, E Zaabout, A Bakheet, M Halawa, I Gad… - Pharmaceutics, 2023 - mdpi.com
Lung cancer is a major public health problem and a leading cause of cancer-related deaths
worldwide. Despite advances in treatment options, the five-year survival rate for lung cancer …

Human skin specific long noncoding RNA HOXC13-AS regulates epidermal differentiation by interfering with Golgi-ER retrograde transport

L Zhang, M Piipponen, Z Liu, D Li, X Bian… - Cell Death & …, 2023 - nature.com
After a skin injury, keratinocytes switch from a state of homeostasis to one of regeneration
leading to the reconstruction of the epidermal barrier. The regulatory mechanism of gene …

Progress in Wound-Healing Products Based on Natural Compounds, Stem Cells, and MicroRNA-Based Biopolymers in the European, USA, and Asian Markets …

GK Srivastava, S Martinez-Rodriguez, NI Md Fadilah… - Polymers, 2024 - mdpi.com
Wounds are breaks in the continuity of the skin and underlying tissues, resulting from
external causes such as cuts, blows, impacts, or surgical interventions. Countless …

Targeting microRNAs as a promising anti-cancer therapeutic strategy against traffic-related air pollution-mediated lung cancer

H Kazemi Shariat Panahi, M Dehhaghi… - Cancer and Metastasis …, 2024 - Springer
Air pollutants are increasingly emitted into the atmosphere because of the high dependency
of humans on fossil-derived fuels. Wind speed and direction assisted high dispersibility and …

MicroRNAs involved in human skin burns, wound healing and scarring

MC Siu, J Voisey, T Zang… - Wound Repair and …, 2023 - Wiley Online Library
MicroRNAs are small, non‐coding RNAs that regulate gene expression, and consequently
protein synthesis. Downregulation and upregulation of miRNAs and their corresponding …

Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors

X Bian, M Piipponen, Z Liu, L Luo, J Geara… - Nature …, 2024 - nature.com
Radiotherapy (RT), a common cancer treatment, unintentionally harms surrounding tissues,
including the skin, and hinders wound healing years after treatment. This study aims to …

Spatiotemporal single-cell roadmap of human skin wound healing

Z Liu, X Bian, L Luo, ÅK Björklund, L Li, L Zhang… - Cell Stem Cell, 2024 - cell.com
Wound healing is vital for human health, yet the details of cellular dynamics and
coordination in human wound repair remain largely unexplored. To address this, we …

[HTML][HTML] Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion

R Bansal, M Torres, M Hunt, N Wang, M Chatzopoulou… - JCI insight, 2024 - ncbi.nlm.nih.gov
Central for wound healing is the formation of granulation tissue, which largely consists of
collagen and whose importance stretches past wound healing, including being implicated in …