Potential of Curcumin in the Management of Skin Diseases

K Kasprzak-Drozd, P Niziński, A Hawrył… - International Journal of …, 2024 - mdpi.com
Curcumin is a polyphenolic molecule derived from the rhizoma of Curcuma longa L. This
compound has been used for centuries due to its anti-inflammatory, antioxidant, and …

Hesperidin-, curcumin-, and amphotericin B-based nano-formulations as potential antibacterials

N Akbar, M Kawish, NA Khan, MR Shah, AM Alharbi… - Antibiotics, 2022 - mdpi.com
To combat the public health threat posed by multiple-drug-resistant (MDR) pathogens, new
drugs with novel chemistry and modes of action are needed. In this study, several drugs …

Ethanol-free extraction of curcumin and antioxidant activity of components from wet Curcuma longa L. by liquefied dimethyl ether

H Kanda, L Zhu, W Zhu, T Wang - Arabian Journal of Chemistry, 2023 - Elsevier
As a solvent, ethanol can extract a wide range of polar substances, but its consumption is
sometimes avoided for religious and cultural reasons. In this study, liquefied dimethyl ether …

Antiamoebic properties of salicylic acid-based deep eutectic solvents for the development of contact lens disinfecting solutions against Acanthamoeba

R Siddiqui, Z Makhlouf, N Akbar, M Khamis… - Molecular and …, 2022 - Elsevier
Acanthamoeba castellanii is a protist pathogen that can cause sight-threatening keratitis and
a fatal infection of the central nervous system, known as granulomatous amoebic …

Novel Plant-Based Metabolites as Disinfectants against Acanthamoeba castellanii

R Siddiqui, N Akbar, B Khatoon, M Kawish, MS Ali… - Antibiotics, 2022 - mdpi.com
Due to global warming, coupled with global water shortages and the reliance of the public
on household water tanks, especially in developing countries, it is anticipated that infections …

Antiamoebic Activity of Imidazothiazole Derivatives against Opportunistic Pathogen Acanthamoeba castellanii

N Akbar, MI El-Gamal, BQ Saeed, CH Oh… - Antibiotics, 2022 - mdpi.com
We examined the antiamoebic effect of several imidazothiazole derivatives on
Acanthamoeba castellanii of the T4 genotype. Trypan blue exclusion assays and …

Novel anti-Acanthamoebic properties of raloxifene sulfonate/sulfamate derivatives

R Siddiqui, MI El-Gamal, S Sajeev, SO Zaraei… - Molecular and …, 2023 - Elsevier
Acanthamoeba are known to cause a vision threatening eye infection typically due to contact
lens wear, and an infection of the central nervous system. The ability of these amoebae to …

Anti-amoebic activity of a series of benzofuran/benzothiophene derivatives against Acanthamoeba castellanii belonging to the T4 genotype

N Akbar, MI El-Gamal, SO Zaraei… - Journal of Applied …, 2023 - academic.oup.com
Aims To determine the anti-amoebic activity of benzofuran/benzothiophene-possessing
compounds against Acanthamoeba castellanii of the T4 genotype. Method and results A …

Role of PCBP2 in regulating nanovesicles loaded with curcumin to mitigate neuroferroptosis in neural damage caused by heat stroke

F Guo, Y Wu, G Wang, J Liu - Journal of Nanobiotechnology, 2024 - Springer
Objective This study aims to elucidate the mechanisms by which nanovesicles (NVs)
transport curcumin (CUR) across the blood–brain barrier to treat hypothalamic neural …

Cinnamic acid and lactobionic acid based nanoformulations as a potential antiamoebic therapeutics

N Akbar, M Kawish, T Jabri, NA Khan, MR Shah… - Experimental …, 2023 - Elsevier
Acanthamoeba castellanii causes granulomatous amoebic encephalitis, an uncommon but
severe brain infection and sight-threatening Acanthamoeba keratitis. Most of the currently …