K Tzavlaki, A Moustakas - Biomolecules, 2020 - mdpi.com
Transforming growth factor-β (TGF-β) represents an evolutionarily conserved family of secreted polypeptide factors that regulate many aspects of physiological embryogenesis …
X Du, L Cai, J Xie, X Zhou - Bone research, 2023 - nature.com
Articular cartilage serves as a low-friction, load-bearing tissue without the support with blood vessels, lymphatics and nerves, making its repair a big challenge. Transforming growth …
GJ Prud'homme, M Kurt, Q Wang - Frontiers in Aging, 2022 - frontiersin.org
The α-Klotho protein (henceforth denoted Klotho) has antiaging properties, as first observed in mice homozygous for a hypomorphic Klotho gene (kl/kl). These mice have a shortened …
A Hata, YG Chen - Cold Spring Harbor perspectives in …, 2016 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) and related growth factors are secreted pleiotropic factors that play critical roles in embryogenesis and adult tissue homeostasis by regulating …
CH Heldin, A Moustakas - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) family members signal via heterotetrameric complexes of type I and type II dual specificity kinase receptors. The activation and stability of the …
S Herbertz, JS Sawyer, AJ Stauber… - Drug design …, 2015 - Taylor & Francis
Transforming growth factor-beta (TGF-β) signaling regulates a wide range of biological processes. TGF-β plays an important role in tumorigenesis and contributes to the hallmarks …
ŁA Poniatowski, P Wojdasiewicz, R Gasik… - Mediators of …, 2015 - Wiley Online Library
The transforming growth factor beta (TGF‐β) family forms a group of three isoforms, TGF‐β1, TGF‐β2, and TGF‐β3, with their structure formed by interrelated dimeric polypeptide chains …
CP Toseland - Journal of chemical biology, 2013 - Springer
This review provides an outline for fluorescent labeling of proteins. Fluorescent assays are very diverse providing the most sensitive and robust methods for observing biological …
Transforming growth factor-beta (TGFβ) is a key regulator of cell fate during embryogenesis and has also emerged as a potent driver of the epithelial-mesenchymal transition during …