Consensus paper: experimental neurostimulation of the cerebellum

LN Miterko, KB Baker, J Beckinghausen, LV Bradnam… - The Cerebellum, 2019 - Springer
The cerebellum is best known for its role in controlling motor behaviors. However, recent
work supports the view that it also influences non-motor behaviors. The contribution of the …

The therapeutic potential of non-invasive and invasive cerebellar stimulation techniques in hereditary ataxias

A Benussi, G Batsikadze, C França, RG Cury, RP Maas - Cells, 2023 - mdpi.com
The degenerative ataxias comprise a heterogeneous group of inherited and acquired
disorders that are characterized by a progressive cerebellar syndrome, frequently in …

Deep brain stimulation of the cerebellum for poststroke motor rehabilitation: from laboratory to clinical trial

CA Wathen, LA Frizon, TK Maiti, KB Baker… - Neurosurgical …, 2018 - thejns.org
Ischemic stroke is a leading cause of disability worldwide, with profound economic costs.
Poststroke motor impairment is the most commonly encountered deficit resulting in …

Functional outcomes of cerebellar malformations

JS Gill, RV Sillitoe - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The cerebellum is well-established as a primary center for controlling sensorimotor
functions. However, recent experiments have demonstrated additional roles for the …

The role of dorsolateral striatum in the effects of deep cerebellar stimulation-mediated motor recovery following ischemic stroke in rodents

HH Chan, ND Mathews, H Khanna, N Mandava… - Experimental …, 2024 - Elsevier
Despite great advances in acute care and rehabilitation, stroke remains the leading cause of
motor impairment in the industrialized world. We have developed a deep brain stimulation …

Lateral cerebellar nucleus stimulation promotes motor recovery and suppresses neuroinflammation in a fluid percussion injury rodent model

HH Chan, CA Wathen, ND Mathews, O Hogue… - Brain Stimulation, 2018 - Elsevier
Background Many traumatic brain injury (TBI) survivors live with persistent disability from
chronic motor deficits despite contemporary rehabilitation services, underscoring the need …

Electrical stimulation of the lateral cerebellar nucleus promotes neurogenesis in rats after motor cortical ischemia

Z Wu, F Sun, Z Li, M Liu, X Tian, D Guo, P Wei… - Scientific reports, 2020 - nature.com
Deep brain stimulation (DBS) has been tentatively explored to promote motor recovery after
stroke. Stroke could transiently activate endogenous self-repair processes, including …

Deep brain stimulation of the interposed nucleus reverses motor deficits and stimulates production of anti-inflammatory cytokines in Ataxia mice

G Kumar, P Asthana, WH Yung, KM Kwan, C Tin… - Molecular …, 2022 - Springer
Cerebellum is one of the major targets of autoimmunity and cerebellar damage that leads to
ataxia characterized by the loss of fine motor coordination and balance, with no treatment …

Deep cerebellar stimulation enhances cognitive recovery after prefrontal traumatic brain injury in rodent

HH Chan, O Hogue, ND Mathews, JG Hunter… - Experimental …, 2022 - Elsevier
Functional outcome following traumatic brain injury (TBI) varies greatly, with approximately
half of those who survive suffering long-term motor and cognitive deficits despite …

Epidural cerebellar stimulation drives widespread neural synchrony in the intact and stroke perilesional cortex

A Abbasi, NP Danielsen, J Leung… - … of neuroengineering and …, 2021 - Springer
Background Cerebellar electrical stimulation has shown promise in improving motor
recovery post-stroke in both rodent and human studies. Past studies have used motor …