Human pluripotent stem cells (hPSCs) have emerged as the most promising cellular source
for cell therapies. To overcome the scale-up limitations of classical 2D culture systems …

Human allogeneic pancreatic islet transplantation is a life-changing treatment for patients
with severe Type 1 Diabetes (T1D) who suffer from hypoglycemia unawareness and high …

Pluripotent stem cells (PSCs) are important for future regenerative medicine therapies.
However, in the production of PSCs and derivatives, the control of culture-induced …

Hepatocytes are of special interest in biomedical research for disease modelling, drug
screening and in vitro toxicology. Human induced pluripotent stem cell (hiPSC)-derived …

Stem cell-based therapies are promising tools for regenerative medicine and require bulk
numbers of high-quality cells. Currently, cells are produced on demand and have a limited …

A reliable suspension-based platform for scaling engineered cardiac tissue (ECT)
production from human induced pluripotent stem cells (hiPSCs) is crucial for regenerative …

Background There is a significant demand for intermediate-scale bioreactors in academic
and industrial institutions to produce cells for various applications in drug screening and/or …

Biobanks of human biosamples and cell lines are indispensable for biomedical research on
human health and disease and for drug development projects. Many human cell line …

The derivation of neuronal lineage cells from human induced pluripotent stem cells (hiPSCs)
marked a milestone in brain research. Since their first advent, protocols have been …

The role of mitochondria in neurodegenerative diseases is crucial, and recent developments
have highlighted its significance in cell therapy. Mitochondrial dysfunction has been …