Nanosafety assessment has experienced an intense era of research during the past
decades driven by a vivid interest of regulators, industry, and society. Toxicological assays …

Ferumoxytol, approved by the US Food and Drug Administration in 2009, is one of the
intravenous iron oxide nanoparticles authorized for the treatment of iron deficiency in …

Few trials have examined rates of hypersensitivity reactions (HSRs) with intravenous iron
formulations used to treat iron deficiency anemia (IDA). This randomized, multicenter …

Abstract Aims (Ultra) Small superparamagnetic iron oxide nanoparticles,(U) SPIO, are
widely used as magnetic resonance imaging contrast media and assumed to be safe for …

With the development of nanotechnology, nanoparticles have been used in various
industries. In medicine, nanoparticles have been used in the diagnosis and treatment of …

Iron deficiency is the leading cause of anaemia and is highly prevalent in patients with
chronic heart failure (CHF). Iron deficiency, with or without anaemia, can be corrected with …

Ferumoxytol is a promising non-gadolinium-based contrast agent with numerous varied
magnetic resonance imaging applications. Previous reviews of vascular applications have …

Abstract Introduction and Objective Intravenous iron preparations rapidly correct iron
deficiency anemia, with the notable drug class effect of rare, yet potentially life-threatening …

This investigation is aimed to develop a novel iron supplement, iron oxide nanoparticles
modified with Angelica sinensis polysaccharide (IONPs-ASP), for the treatment of iron …

Vascular dysfunction, characterized by changes in anatomy, hemodynamics, and molecular
expressions of vasculatures, is closely linked to the onset and development of diseases …