Obesity-related co-morbidities decrease life quality, reduce working ability, and lead to early
death. In the adult population, eating addiction manifests with excessive food consumption …

Klotho is a life extension factor that has the ability to regulate the function of GluN2B-
containing N-methyl-d-aspartate receptors (NMDARs), whose dysfunction in the nucleus …

Major depressive disorder (MDD), a common psychiatric condition, adversely affects
patients' moods and quality of life. Despite the development of various treatments, many …

Neurosurgical interventions including deep brain stimulation (DBS) and capsulotomy have
been demonstrated effective for refractory obsessive-compulsive disorder (OCD), although …

The ventromedial prefrontal cortex (vmPFC) to nucleus accumbens (NAc) circuit has been
implicated in impulsive reward-seeking. This disinhibition has been implicated in obesity …

Temporal interference electrical neurostimulation (TI) is a relatively new method of non-
invasive neurostimulation that may be able to stimulate deep brain regions without …

Abstract Introduction Nucleus accumbens (NAc), a crucial component of the brain's reward
network, plays a role in reward-related behaviors like substance use. However, limited …

Background: Nucleus accumbens (NAc) is a brain structure with a well-established role in
the brain reward processing system. Altered function of the NAc is shown to have a role in …

Psychosocial chronic stress is a critical risk factor for the development of mood disorders.
However, little is known about the consequences of acute stress in the context of chronic …

Deep brain stimulation (DBS) has been shown to be an effective treatment for movement
disorders and it is now being extended to the treatment of psychiatric disorders. Functional …