Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

Extracellular vesicles (EV) are secretory membranous elements used by cells to transport
proteins, lipids, mRNAs, and microRNAs (miRNAs). While their existence has been known …

Although immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment,
many patients do not respond or develop resistance to ICB. N6-methylation of adenosine …

RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …

In animals, P-bodies or GW-bodies appear to cause the congregation of proteins involved in
microRNA (miRNA)-mediated post-transcriptional silencing. The localization of P-bodies …

Lung adenocarcinoma (LUAD) is the main subtype of lung cancer. In this study, we found
that RBP Mex3a was significantly upregulated in LUAD tissues and elevated Mex3a …

Although mammalian long non-coding (lnc) RNAs are best known for modulating
transcription, their post-transcriptional influence on mRNA splicing, stability and translation …

MicroRNAs (miRNAs) are versatile regulators of gene expression with profound implications
for human disease including atherosclerosis, but whether they can exert posttranslational …

Highly proliferative Lgr5+ stem cells maintain the intestinal epithelium and are thought to be
largely homogeneous. Although quiescent intestinal stem cell (ISC) populations have been …

Epithelial ovarian cancer is a highly heterogeneous and malignant female cancer with an
overall low survival rate. Mutations in p53 are prevalent in the major ovarian cancer …