The regulation of cartilage extracellular matrix homeostasis in joint cartilage degeneration and regeneration

Z Peng, H Sun, V Bunpetch, Y Koh, Y Wen, D Wu… - Biomaterials, 2021 - Elsevier
Osteoarthritis (OA) is a major cause of disability and socioeconomic loss worldwide.
However, the current pharmacological approaches used to treat OA are largely palliative …

Cartilage diseases

Y Krishnan, AJ Grodzinsky - Matrix Biology, 2018 - Elsevier
Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human
body including bearing loads in articular joints and intervertebral discs, providing joint …

Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms

A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

The extracellular matrix: its composition, function, remodeling, and role in tumorigenesis

K Dzobo, C Dandara - Biomimetics, 2023 - mdpi.com
The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

Myocardial extracellular matrix: an ever-changing and diverse entity

M Rienks, AP Papageorgiou… - Circulation …, 2014 - Am Heart Assoc
The cardiac extracellular matrix (ECM) is a complex architectural network consisting of
structural and nonstructural proteins, creating strength and plasticity. The nonstructural …

Biomaterials to mimic and heal connective tissues

BR Freedman, DJ Mooney - Advanced Materials, 2019 - Wiley Online Library
Connective tissue is one of the four major types of animal tissue and plays essential roles
throughout the human body. Genetic factors, aging, and trauma all contribute to connective …

Asthma: from bronchoconstriction to airways inflammation and remodeling

J Bousquet, PK Jeffery, WW Busse… - American journal of …, 2000 - atsjournals.org
Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

Natural polymers: polysaccharides and their derivatives for biomedical applications

A Aravamudhan, DM Ramos, AA Nada… - Natural and synthetic …, 2014 - Elsevier
Several polymers of both natural and synthetic origin have been used for a variety of
biomedical applications including pharmaceutical preparations, drug targeting, imaging …

The physiology of the lymphatic system

MA Swartz - Advanced drug delivery reviews, 2001 - Elsevier
This paper presents an overview of the anatomy, physiology, and biology of the lymphatic
system specifically relevant to lymphatic drug delivery. We will briefly review the classic fluid …

Biomaterials and tissue engineering approaches using glycosaminoglycans for tissue repair: Lessons learned from the native extracellular matrix

R Menezes, R Vincent, L Osorno, P Hu, TL Arinzeh - Acta biomaterialia, 2023 - Elsevier
Glycosaminoglycans (GAGs) are an important component of the extracellular matrix as they
influence cell behavior and have been sought for tissue regeneration, biomaterials, and …