Activation of the interleukin-23/interleukin-17 signalling pathway in autoinflammatory and autoimmune uveitis

Z Zhong, G Su, A Kijlstra, P Yang - Progress in retinal and eye research, 2021 - Elsevier
Uveitis is a group of diseases characterized by intraocular inflammation, of which some are
driven by autoinflammatory or autoimmune responses, such as Vogt-Koyanagi-Harada …

Vogt-Koyanagi-Harada disease: review of a rare autoimmune disease targeting antigens of melanocytes

MM Lavezzo, VM Sakata, C Morita… - Orphanet Journal of …, 2016 - Springer
Abstract Vogt-Koyanagi-Harada disease (VKHD) is a rare granulomatous inflammatory
disease that affects pigmented structures, such as eye, inner ear, meninges, skin and hair …

The cytokine IL-17A limits Th17 pathogenicity via a negative feedback loop driven by autocrine induction of IL-24

WP Chong, MJ Mattapallil, K Raychaudhuri, SJ Bing… - Immunity, 2020 - cell.com
Dysregulated Th17 cell responses underlie multiple inflammatory and autoimmune
diseases, including autoimmune uveitis and its animal model, EAU. However, clinical trials …

Microbiota-dependent activation of an autoreactive T cell receptor provokes autoimmunity in an immunologically privileged site

R Horai, CR Zárate-Bladés, P Dillenburg-Pilla, J Chen… - Immunity, 2015 - cell.com
Activated retina-specific T cells that have acquired the ability to break through the blood-
retinal barrier are thought to be causally involved in autoimmune uveitis, a major cause of …

Vogt-Koyanagi-Harada disease: novel insights into pathophysiology, diagnosis and treatment

L Du, A Kijlstra, P Yang - Progress in retinal and eye research, 2016 - Elsevier
Abstract Vogt-Koyanagi-Harada (VKH) disease is one of the major vision-threatening
diseases in certain populations, such as Asians, native Americans, Hispanics and Middle …

Vogt-Koyanagi-Harada disease: the step-by-step approach to a better understanding of clinicopathology, immunopathology, diagnosis, and management: a brief …

CA Urzua, CP Herbort Jr, M Takeuchi… - Journal of Ophthalmic …, 2022 - Springer
Abstract Background Appraisals of Vogt-Koyanagi-Harada disease (VKH) have become
progressively more complete, since its first description in 1906. The availability of new …

Cytokines that modulate the differentiation of Th17 cells in autoimmune uveitis

K Guo, X Zhang - Journal of immunology research, 2021 - Wiley Online Library
Increasing evidence has suggested that T helper 17 (Th17) cells play a central role in the
pathogenesis of ocular immune disease. The association between pathogenic Th17 cells …

Increased serum levels of TNF-α and decreased serum levels of IL-27 in patients with Parkinson disease and their correlation with disease severity

E Kouchaki, RD Kakhaki, OR Tamtaji… - Clinical neurology and …, 2018 - Elsevier
Objectives: Immunological basis of neurodegenerative diseases including Alzheimer and
Parkinson disease (PD) has some important roles in their pathogenesis. There are …

Activation of the aryl hydrocarbon receptor affects activation and function of human monocyte-derived dendritic cells

C Wang, Z Ye, A Kijlstra, Y Zhou… - Clinical & Experimental …, 2014 - academic.oup.com
Aryl hydrocarbon receptor (AhR) is well known for mediating the toxic effects of dioxin-
containing pollutants, but has also been shown to be involved in the natural regulation of the …

Effects of Fe3O4 Magnetic Nanoparticles on A549 Cells

M Watanabe, M Yoneda, A Morohashi, Y Hori… - International journal of …, 2013 - mdpi.com
Fe3O4 magnetic nanoparticles (MgNPs-Fe3O4) are widely used in medical applications,
including magnetic resonance imaging, drug delivery, and in hyperthermia. However, the …