Role of mast cells activation in the tumor immune microenvironment and immunotherapy of cancers

X Guo, M Sun, P Yang, X Meng, R Liu - European Journal of Pharmacology, 2023 - Elsevier
The mast cell is an important cellular component that plays a crucial role in the crosstalk
between innate and adaptive immune responses within the tumor microenvironment (TME) …

[HTML][HTML] Innate immune cells in melanoma: Implications for immunotherapy

M Trocchia, A Ventrici, L Modestino… - International Journal of …, 2024 - mdpi.com
The innate immune system, composed of neutrophils, basophils, eosinophils, myeloid-
derived suppressor cells (MDSCs), macrophages, dendritic cells (DCs), mast cells (MCs) …

Melanomas and mast cells: an ambiguous relationship

LM Kohl, TL Sumpter - Melanoma Research, 2024 - journals.lww.com
Mast cells (MCs) accumulate in a broad range of tumors, including melanomas. While MCs
are potent initiators of immunity in infection, and in allergic inflammation, the function of MCs …

[HTML][HTML] Downregulation of ABLIM3 confers to the metastasis of neuroblastoma via regulating the cell adhesion molecules pathway

B Gong, T Qu, J Zhang, Y Jia, Z Song, C Chen… - Computational and …, 2024 - Elsevier
Neuroblastoma (NB) is the most prevalent extracranial solid tumor in pediatric patients, and
its treatment failure often associated with metastasis. In this study, LASSO, SVM-RFE, and …

Mast cell proteases and metastasis

D Ribatti - Pathology-Research and Practice, 2024 - Elsevier
Mast cells exert multiple roles beyond their classical role in IgE-mediated allergic reactions.
These cells secrete pro-inflammatory and anti-inflammatory agents and change from …