[HTML][HTML] Therapeutic potential of combating cancer by restoring wild-type p53 through mRNA nanodelivery
D Kamath, T Iwakuma, SH Bossmann - … : Nanotechnology, Biology and …, 2024 - Elsevier
Among the tumor suppressor genes, TP53 is the most frequently mutated in human cancers,
and most mutations are missense mutations causing production of mutant p53 (mutp53) …
and most mutations are missense mutations causing production of mutant p53 (mutp53) …
AI-guided identification of risk variants for adrenocortical tumours in TP53 p. R337H carrier children: a genetic association study
BC Figueiredo, F Dupont, G Portelli… - The Lancet Regional …, 2024 - thelancet.com
Background Adrenocortical tumours (ACT) in children are part of the Li-Fraumeni cancer
spectrum and are frequently associated with a germline TP53 pathogenic variant. TP53 p …
spectrum and are frequently associated with a germline TP53 pathogenic variant. TP53 p …
[PDF][PDF] Targeting P53 Gene in Breast Cancer
Infectious diseases and breast cancer rely heavily on p53, a tumor suppressor that protects
genetic integrity. It is present on chromosome 17p13 and controls angiogenesis …
genetic integrity. It is present on chromosome 17p13 and controls angiogenesis …