Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives

M González-Vallinas, M González-Castejón… - Nutrition …, 2013 - academic.oup.com
The population is aging. Over the coming years, the incidence of age-related chronic
diseases such as cancer is expected to continue to increase. Phytochemicals, which are non …

Soy isoflavones and prostate cancer: a review of molecular mechanisms

AM Mahmoud, W Yang, MC Bosland - The Journal of steroid biochemistry …, 2014 - Elsevier
Soy isoflavones are dietary components for which an association has been demonstrated
with reduced risk of prostate cancer (PCa) in Asian populations. However, the exact …

Genistein: A focus on several neurodegenerative diseases

R Li, M Robinson, X Ding, T Geetha… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative diseases are caused by the progressive loss of function or structure of
nerve cells in the central nervous system. The most common neurodegenerative diseases …

Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid‐Based Delivery Systems

L Mouhid, M Corzo-Martínez, C Torres… - Journal of …, 2017 - Wiley Online Library
Cancer is among the leading causes of morbidity and mortality worldwide. Many of the
chemotherapeutic agents used in cancer treatment exhibit cell toxicity and display …

[HTML][HTML] Therapeutic targeting of replicative immortality

P Yaswen, KL MacKenzie, WN Keith, P Hentosh… - Seminars in cancer …, 2015 - Elsevier
One of the hallmarks of malignant cell populations is the ability to undergo continuous
proliferation. This property allows clonal lineages to acquire sequential aberrations that can …

Herbal honey preparations of Curcuma xanthorriza and black cumin protect against carcinogenesis through antioxidant and immunomodulatory activities in Sprague …

T Hidayati, I Indrayanti, E Darmawan, A Akrom - Nutrients, 2023 - mdpi.com
Background: Traditionally, Curcuma xanthorriza (CX), black cumin seed (BC), and honey
have been used by the Indonesian people as medicinal ingredients to treat various health …

The antigenotoxic potential of dietary flavonoids

VS Luca, A Miron, AC Aprotosoaie - Phytochemistry Reviews, 2016 - Springer
Human exposure to genotoxic agents has dramatically increased. Both endogenous
(reactive species generated during physiological and pathological processes) and …

Deficiency in the nuclear‐related factor erythroid 2 transcription factor (N rf1) leads to genetic instability

DH Oh, D Rigas, A Cho, JY Chan - The FEBS journal, 2012 - Wiley Online Library
Nuclear factor erythroid‐derived 2‐related factor 1 (N rf1) regulates cellular stress response
genes, and has also been suggested to play a role in other cellular processes. We …

Guidance for the use and interpretation of assays for monitoring anti-genotoxicity

V Yadav, JL Fuentes, A Krishnan, N Singh, D Vohora - Life Sciences, 2024 - Elsevier
Since DNA damage can occur spontaneously or be produced by the environmental
genotoxins in living cells, it is important to investigate compounds that can reverse or protect …