The goals of the End TB strategy, which aims to achieve a 90% reduction in tuberculosis
(TB) incidence and a 95% reduction in TB mortality by 2035, will not be achieved without …

Background Drug-resistant tuberculosis burdens fragile health systems in sub-Saharan
Africa (SSA), complicated by high prevalence of HIV. Several African countries reported …

SETTING: In 2005, in response to the increasing prevalence of rifampicin-resistant
tuberculosis (RR-TB) and poor treatment outcomes, Rwanda initiated the programmatic …

The accessibility, sustainability and scale-up of new diagnostic technologies are lagging
behind and more efforts are needed. In addition, we need high-quality information on safety …

Socio-economic issues, such as poverty levels and high levels of unemployment are among
the impediments to accessing healthcare services which results in poor health outcomes. In …

To reduce the incidence of tuberculosis, it is insufficient to simply understand the dynamics
of tuberculosis transmission. Rather, we must design and rigorously evaluate interventions …

Background Low-and middle-income countries (LMICs) now have increasing access to
cancer medicines, which are being integrated into national cancer control programs. This …

The Lesotho guidelines for the management of drug-resistant tuberculosis (TB) recommend
initiation of patients diagnosed with rifampicin resistant (RR)-TB on a standardized drug …

Background. Rifampicin resistance (RR) is associated with mortality among tuberculosis
(TB) patients coinfected with HIV. We compared the prevalence of RR among TB patients …

Background A delayed initiation of tuberculosis treatment results in high morbidity, mortality,
and increased person-to-person transmissions. The aim of this study was to assess …