Long-term effects of exercise and physical therapy in people with Parkinson disease

MK Mak, IS Wong-Yu, X Shen, CL Chung - Nature Reviews Neurology, 2017 - nature.com
Parkinson disease (PD) is a progressive, neurodegenerative movement disorder with
symptoms reflecting various impairments and functional limitations, such as postural …

Rehabilitation for Parkinson's disease: current outlook and future challenges

G Abbruzzese, R Marchese, L Avanzino… - Parkinsonism & related …, 2016 - Elsevier
Rehabilitation is considered as an adjuvant to pharmacological and surgical treatments for
Parkinson's disease (PD) to maximize functional ability and minimize secondary …

Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease

GM Petzinger, BE Fisher, S McEwen, JA Beeler… - The Lancet …, 2013 - thelancet.com
Exercise interventions in individuals with Parkinson's disease incorporate goal-based motor
skill training to engage cognitive circuitry important in motor learning. With this exercise …

The neuroprotective effects of exercise: maintaining a healthy brain throughout aging

LM Vecchio, Y Meng, K Xhima, N Lipsman… - Brain …, 2018 - content.iospress.com
Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

The benefits and mechanisms of exercise training for Parkinson's disease

YS Feng, SD Yang, ZX Tan, MM Wang, Y Xing, F Dong… - Life sciences, 2020 - Elsevier
Parkinson's disease (PD) is a significantly progressive neurodegenerative disease
characterised by both motor and nonmotor disorders. The main pathological characteristics …

Nonpharmacological treatments for patients with Parkinson's disease

BR Bloem, NM de Vries, G Ebersbach - Movement Disorders, 2015 - Wiley Online Library
Since 2013, a number of studies have enhanced the literature and have guided clinicians on
viable treatment interventions outside of pharmacotherapy and surgery. Thirty‐three …

[HTML][HTML] Neuroprotective strategies for retinal disease

MT Pardue, RS Allen - Progress in retinal and eye research, 2018 - Elsevier
Diseases that affect the eye, including photoreceptor degeneration, diabetic retinopathy, and
glaucoma, affect 11.8 million people in the US, resulting in vision loss and blindness. Loss of …

Exercise increases caudate dopamine release and ventral striatal activation in Parkinson's disease

MA Sacheli, JL Neva, B Lakhani, DK Murray… - Movement …, 2019 - Wiley Online Library
Background The objective of this study was to examine the effects of aerobic exercise on
evoked dopamine release and activity of the ventral striatum using positron emission …

The effects of highly challenging balance training in elderly with Parkinson's disease: a randomized controlled trial

D Conradsson, N Löfgren, H Nero… - … and neural repair, 2015 - journals.sagepub.com
Background. Highly challenging exercises have been suggested to induce neuroplasticity in
individuals with Parkinson's disease (PD); however, its effect on clinical outcomes remains …

Treadmill training for patients with Parkinson's disease

J Mehrholz, J Kugler, A Storch, M Pohl… - Cochrane database …, 2015 - cochranelibrary.com
Background Treadmill training is used in rehabilitation and is described as improving gait
parameters of patients with Parkinson's disease. Objectives To assess the effectiveness of …