Semisupervised Contrastive Learning for Bioactivity Prediction Using Cell Painting Image Data

D Bushiri Pwesombo, C Beese… - Journal of Chemical …, 2024 - ACS Publications
Morphological profiling has recently demonstrated remarkable potential for identifying the
biological activities of small molecules. Alongside the fully supervised and self-supervised …

[HTML][HTML] Clinical efficacy and safety of flunarizine tablets combined with betahistine hydrochloride tablets in patients with vertebrobasilar insufficiency vertigo

S Meng, Q Liu, L Zhang - American Journal of Translational …, 2022 - ncbi.nlm.nih.gov
Objective: To explore the clinical efficacy and safety of betahistine hydrochloride tablets in
patients with vertebrobasilar insufficiency vertigo (VBIV). Methods: A total of 133 patients …

Paeoniflorin inhibits Th1 and Th17 cells in gut-associated lymphoid tissues to produce anti-arthritis activities

F Fei, L Aa, Q Qi, R Sun, C Yan, J Aa, G Wang - Inflammopharmacology, 2019 - Springer
Paeoniflorin shows distinct anti-arthritis and immunoregulatory activities, but its rather low
bioavailability via oral administration greatly challenges its known mechanism of in vivo …

Effect of betahistine on pro‐inflammatory cytokine expression in autoimmune inner ear disease and Meniere's disease patients

I Yellin, S Pathak, A Vambutas - Laryngoscope Investigative …, 2024 - Wiley Online Library
Objective Betahistine is a partial H1 receptor agonist and a potent H3 receptor antagonist
commonly used for the treatment of MD and peripheral vertigo. The aim of this study was to …

Agent Clustering Strategy Based on Metabolic Flux Distribution and Transcriptome Expression for Novel Drug Development

Y Ruan, XH Chen, F Jiang, YG Liu, XL Liang, BM Lv… - Biomedicines, 2021 - mdpi.com
The network module-based method has been used for drug repositioning. The traditional
drug repositioning method only uses the gene characteristics of the drug but ignores the …

[PDF][PDF] Piracetam and betahistine: possible mechanisms of endothelioprotection

AS Solgalova, VO Soldatov, MA Pershina… - Kursk Scientific and …, 2018 - kursk-vestnik.ru
Betahistine and Piracetam are routine drugs in neurological practice, which are used to
correct cerebral circulation disorders. The clinical efficacy of these drugs can be caused not …

[HTML][HTML] In Vitro Physiological Effects of Betahistine on Cell Lines of Various Origins

AH Kepekci, Gİ Gündoğan, KIG Cenk - Turkish Journal of …, 2021 - ncbi.nlm.nih.gov
Objectives: Betahistine is a histamine analog commonly prescribed for symptomatic
treatment of vertiginous symptoms. In vitro studies have shown that betahistine was not toxic …

Пирацетам и бетагистин: возможные механизмы эндотелиопротекции

АС Солгалова, ВО Солдатов, МА Першина… - Человек и его …, 2018 - cyberleninka.ru
Бетагистин и пирацетам являются рутинными препаратами в неврологической
практике, которые используются при коррекции дисциркуляторных нарушений …

In vitro physiological effects of betahistine on cell lines of various origins Betahistinin farklı orijinlere sahip hücreler üzerindeki in vitro fizyolojik etkileri

A Kepekçi, G Gündoğan, C Kig - Turkish Journal of …, 2021 - avesis.yeniyuzyil.edu.tr
Objectives: Betahistine is a histamine analog commonly prescribed for symptomatic
treatment of vertiginous symptoms. In vitro studies have shown that betahistine was not toxic …

Betahistinin Farklı Orijinlere Sahip Hücreler Üzerindeki İn Vitro Fizyolojik Etkileri

A KEPEKÇİ, G GÜNDOĞAN… - Turkish Journal of …, 2021 - avesis.yeniyuzyil.edu.tr
Amaç: Betahistin vertigo semptomlarının semptomatik tedavisi amacıyla sıklıkla reçete
edilen bir histamin analoğudur. İn vitro çalışmalar, betahistinin reçete edilen dozlarda nazal …