Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

Cells must alter their expression profiles and morphological characteristics but also reshape
the extracellular matrix (ECM) to fulfill their functions throughout their lifespan. Matrix …

Rheumatoid arthritis (RA) represents one of the best examples of circadian fluctuations in
disease severity. Patients with RA experience stiffness, pain, and swelling in afflicted joints …

Bone regeneration remains a great clinical challenge. Low intensity near-infrared (NIR) light
showed strong potential to promote tissue regeneration, offering a promising strategy for …

BMAL1 is a core component of the circadian clock loop, which directs the sophisticated
circadian expression of clock-controlled genes. Skeletal Bone development is a complex …

The oral and maxillofacial organs play vital roles in chewing, maintaining facial beauty, and
speaking. Almost all physiological processes display circadian rhythms that are driven by …

The circadian clock is a master regulator in coordinating daily oscillations of physiology and
behaviors. Nevertheless, how the circadian rhythm affects endochondral ossification is …

Objective Chondrogenesis and endochondral ossification in mandibular condyle play
crucial roles in maxillofacial morphogenesis and function. Circadian regulator brain and …

Objectives Skeletal mandibular hypoplasia (SMH), a common type of developmental
deformities, results in impaired aesthetics of facial profile, occlusal dysfunction and poor life …

Secretory glands, responsible for tears and saliva production, play essential roles in
maintaining ocular and oral well-being. Disruptions in gland secretion can arise from various …