Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

Conspectus DNA-based enzymes, or DNAzymes, are not known to exist in Nature but can
be isolated from random-sequence DNA pools using test tube selection techniques. Since …

On the basis of the remarkable difference in affinity of graphene (GO) with ssDNA containing
a different number of bases in length, we for the first time report a GO–DNAzyme based …

A catalytic beacon sensor for Pb2+ has been developed based on the first DNAzyme
discovered in the field, and such a sensor has shown a much higher metal ion selectivity (40 …

In cells, DNA typically consists of two antiparallel strands arranged in a double-helical
structure, which is central to its fundamental role in storing and transmitting genetic …

Deoxyribozymes or DNAzymes are single-stranded catalytic DNA molecules that are
obtained by combinatorial in vitro selection methods. Initially conceived to function as gene …

Deoxyribozymes (DNA catalysts) have been reported for cleavage of RNA phosphodiester
linkages, but cleaving peptide or DNA phosphodiester linkages is much more challenging …

Enzymes play a crucial role in all living organisms by accelerating the rates of a myriad of
biochemical reactions that are necessary to sustain life. Although the vast majority of known …

Cadmium, mercury, and lead are collectively banned by many countries and regions in
electronic devices due to their extremely high toxicity. To date, no sensing method can …

The selection of modified DNAzymes represents an important endeavor in expanding the
chemical and catalytic properties of catalytic nucleic acids. Few examples of such exist and …