Vascular inflammation and oxidative stress: major triggers for cardiovascular disease

S Steven, K Frenis, M Oelze, S Kalinovic… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

[HTML][HTML] Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication

JB Funcke, PE Scherer - Journal of lipid research, 2019 - ASBMB
The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

[HTML][HTML] DPP4 in diabetes

D Röhrborn, N Wronkowitz, J Eckel - Frontiers in immunology, 2015 - frontiersin.org
Dipeptidyl-peptidase 4 (DPP4) is a glycoprotein of 110 kDa, which is ubiquitously expressed
on the surface of a variety of cells. This exopeptidase selectively cleaves N-terminal …

The pathophysiology of hypertension in patients with obesity

VG DeMarco, AR Aroor, JR Sowers - Nature Reviews Endocrinology, 2014 - nature.com
The combination of obesity and hypertension is associated with high morbidity and mortality
because it leads to cardiovascular and kidney disease. Potential mechanisms linking …

[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach… - Redox biology, 2017 - Elsevier
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Dipeptidyl peptidase 4 inhibitors and their potential immune modulatory functions

S Shao, QQ Xu, X Yu, R Pan, Y Chen - Pharmacology & therapeutics, 2020 - Elsevier
Abstract Dipeptidyl peptidase 4 (DPP4) inhibitors (DPP4is) are oral anti-diabetic drugs
(OADs) for the treatment of type 2 diabetes mellitus (T2DM) through inhibiting the …

[PDF][PDF] Сахарный диабет 2 типа

АС Аметов - Проблемы и решения, 2014 - e-library.sammu.uz
Аннотация Современная диабетология обращает самое серьезное внимание на
метаболизм жировой ткани потому, что жировая ткань очень тесно связана с …

[HTML][HTML] Role of epicardial adipose tissue in cardiovascular diseases: a review

M Konwerski, A Gąsecka, G Opolski, M Grabowski… - Biology, 2022 - mdpi.com
Simple Summary Cardiovascular diseases (CVDs) are the leading causes of death
worldwide. Epicardial adipose tissue (EAT) is one of the most important risk factors for …

[HTML][HTML] Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies

A Daiber, S Chlopicki - Free Radical Biology and Medicine, 2020 - Elsevier
According to the latest Global Burden of Disease Study data, non-communicable diseases in
general and cardiovascular disease (CVD) in particular are the leading cause of premature …

Cardiovascular biology of the incretin system

JR Ussher, DJ Drucker - Endocrine reviews, 2012 - academic.oup.com
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that enhances glucose-stimulated
insulin secretion and exerts direct and indirect actions on the cardiovascular system. GLP-1 …