A systematic review and meta‐regression analysis of prophylactic gabapentin for postoperative pain

B Doleman, TP Heinink, DJ Read, RJ Faleiro… - …, 2015 - Wiley Online Library
Summary We searched MEDLINE, Embase, CINAHL, AMED and CENTRAL databases until
December 2014 and included 133 randomised controlled trials of peri‐operative gabapentin …

Gabapentin and pregabalin for the acute post-operative pain management. A systematic-narrative review of the recent clinical evidences

M Dauri, S Faria, A Gatti, L Celidonio… - Current drug …, 2009 - ingentaconnect.com
Background: Gabapentin and pregabalin inhibit Ca2+ currents via high-voltage-activated
channels containing the α2δ-1 subunit, reducing neurotransmitter release and attenuating …

Perioperative adverse events attributed to α2-adrenoceptor agonists in patients not at risk of cardiovascular events: systematic review and meta-analysis

M Demiri, T Antunes, D Fletcher, V Martinez - British Journal of Anaesthesia, 2019 - Elsevier
Background Several systematic reviews have reported the benefits of perioperative α2-
adrenoceptor agonist use for various conditions, but safety evidence is poorly documented …

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery

D Duncan, A Sankar, WS Beattie… - Cochrane Database …, 2018 - cochranelibrary.com
Background The surgical stress response plays an important role on the pathogenesis of
perioperative cardiac complications. Alpha‐2 adrenergic agonists attenuate this response …

Pain experienced by patients during minimal-invasive ultrasound-guided breast biopsy: vacuum-assisted vs core-needle procedure

B Szynglarewicz, R Matkowski, P Kasprzak… - European Journal of …, 2011 - Elsevier
AIMS: To evaluate comparatively the pain associated with ultrasound-guided core-needle
(CN) and vacuum-assisted (VA) biopsy for non-palpable breast lesions. METHODS: 723 …

Comparative study among gabapentin, midazolam and granisetron for prevention of postoperative nausea and vomiting after middle ear surgery

AMS Al-Najjar, DESM Soud, HNF Hassan… - The Egyptian Journal …, 2022 - journals.ekb.eg
Background: Postoperative nausea and vomiting (PONV) is the one of the most unpleasant
complications. PONV is more distressing for patients than pain. Objective: The aim of the …

[PDF][PDF] A synergistic approach to evaluate the anti-nociceptive activity of a GABA agonist with opioids in albino mice

GF Britto, K Subash, NJ Rao, BV Cheriyan… - J Clin Diagn …, 2012 - academia.edu
Opioids constitute the first-line treatment for pain and they provide a potent analgesic effect,
but they are also responsible for various adverse effects such as nausea, vomiting, sedation …

A comparative evaluation of oral clonidine and oral gabapentin as a premedication on postoperative analgesia duration in patients undergoing spinal anesthesia

R Das, K Paul, PK Halder, A Choudhury… - Muller Journal of …, 2022 - journals.lww.com
Materials and Methods: A prospective, double-blinded study was conducted in randomly
selected 100 patients undergoing spinal anesthesia for any surgery (excluding cesarean …

[PDF][PDF] Effect of Pre-operative Oral Gabapentin on Postoperative Pain in Opioid-dependent Patients Undergoing Orthopedic Surgeries of the Lower Extremity: A …

S Khademi, A Farbood, E Sabokseir, M Ghani - J Pain Relief, 2018 - academia.edu
Background: The aim of this study is to investigate the effect of a single dose of gabapentin,
1200 mg and one hour before surgery on postoperative pain in opioid-dependent patients …

[PDF][PDF] Comparison of Postoperative Mean Morphine Consumption in patients given Preoperative Gabapentin and Placebo undergoing Major Laparotomies for Lower …

T IQBAL, R FAROOQI, MS MEHMOOD, ZY BHATTI… - pjmhsonline.com
Aim: Comparison of postoperative mean morphine consumption in patients given
preoperative gabapentin and placebo undergoing major laparotomies for lower abdomen …