Causes of genome instability: the effect of low dose chemical exposures in modern society

SAS Langie, G Koppen, D Desaulniers… - …, 2015 - academic.oup.com
Genome instability is a prerequisite for the development of cancer. It occurs when genome
maintenance systems fail to safeguard the genome's integrity, whether as a consequence of …

Comet assay to measure DNA repair: approach and applications

A Azqueta, J Slyskova, SAS Langie… - Frontiers in …, 2014 - frontiersin.org
Cellular repair enzymes remove virtually all DNA damage before it is fixed; repair therefore
plays a crucial role in preventing cancer. Repair studied at the level of transcription …

An optimized comet-based in vitro DNA repair assay to assess base and nucleotide excision repair activity

S Vodenkova, A Azqueta, A Collins, M Dusinska… - Nature protocols, 2020 - nature.com
This optimized protocol (including links to instruction videos) describes a comet-based in
vitro DNA repair assay that is relatively simple, versatile, and inexpensive, enabling the …

From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?

KS vel Szic, K Declerck, M Vidaković… - Clinical …, 2015 - Springer
The progressively older population in developed countries is reflected in an increase in the
number of people suffering from age-related chronic inflammatory diseases such as …

Epigenetic regulation of DNA repair genes and implications for tumor therapy

M Christmann, B Kaina - Mutation Research/Reviews in Mutation Research, 2019 - Elsevier
DNA repair represents the first barrier against genotoxic stress causing metabolic changes,
inflammation and cancer. Besides its role in preventing cancer, DNA repair needs also to be …

[HTML][HTML] From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?

K Declerck, M Vidaković… - Clinical …, 2015 - clinicalepigeneticsjournal …
The progressively older population in developed countries is reflected in an increase in the
number of people suffering from age-related chronic inflammatory diseases such as …

[HTML][HTML] Yoga and its impact on chronic inflammatory autoimmune arthritis

S Gautam, U Kumar, R Dada - Frontiers in Bioscience-Elite, 2020 - imrpress.com
Rheumatoid arthritis (RA) is one of the most common chronic inflammatory autoimmune
diseases, which adversely affects the quality of life. RA is a disease of unknown etiology …

[HTML][HTML] Interaction between peroxisome proliferator-activated receptors and cannabidiol in the gut of chickens applied to different challenge conditions

D Szkopek, M Mendel, M Kinsner, B Fotschki… - International Journal of …, 2024 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are important targets for cannabidiol
(CBD), which mediate many of its biological actions. The hypothesis of the present research …

The effect of different dietary ratios of lysine and arginine in diets with high or low methionine levels on oxidative and epigenetic DNA damage, the gene expression of …

K Ognik, P Konieczka, D Mikulski, J Jankowski - Veterinary research, 2020 - Springer
Two experiments were performed to investigate the effect of different ratios of arginine (Arg)
to lysine (Lys) in diets with low (30% Lys; Experiment 1) and high (45% Lys; Experiment 2) …

Role of polyphenols in the metabolism of the skeletal system in humans and animals–a review

G Skiba, S Raj, M Sobol, P Kowalczyk… - Annals of Animal …, 2021 - sciendo.com
♦ Corresponding author: eugeniusz. grela@ up. lublin. pl abstract polyphenols are a group
of compounds arousing enormous interest due to their multiple effects on both human and …